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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ketamine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ketamine
UMLS_CUI
  • C0022614
CAS_Registry
  • 6740-88-1
FDA_UNII_Code
  • 690G0D6V8H
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to cause a loss of feeling and awareness and to induce sleep in patients having surgery. It is also being studied in the treatment of nerve pain caused by chemotherapy. Ketamine blocks pathways to the brain that are involved in sensing pain. It is a type of general anesthetic.NCI-GLOSS
Chemical_Formula
  • C13H16ClNO
Legacy_Concept_Name
  • Ketamine
CHEBI_ID
  • CHEBI:6121
FULL_SYN
  • KETAMINEPTFDA690G0D6V8H
  • ketaminePTNCI-GLOSSCDR0000557357
  • KetaminePTNCI
DEFINITION
  • A cyclohexanone derivative with analgesic and anesthetic properties. Although its mechanism of action is not well understood, ketamine appears exerts complex pharmacological actions including inhibition of biogenic amine uptake, binding to opioid receptors, and inhibition of N-methyl D-aspartate (NMDA) receptors. Because of the involvement of spinal NMDA receptors in the process of central sensitization, this agent may reduce pain perception and induce sedation.NCI
code
  • C61797
sameAs
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