About: Ketamine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ketamine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Ketamine Hydrochloride
UMLS_CUI
  • C0700541
CAS_Registry
  • 1867-66-9
FDA_UNII_Code
  • O18YUO0I83
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to cause a loss of feeling and awareness and to induce sleep in patients having surgery. It is also being studied in the treatment of nerve pain caused by chemotherapy. Ketalar blocks pathways to the brain that are involved in sensing pain. It is a type of general anesthetic.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 452041
PDQ_Closed_Trial_Search_ID
  • 452041
Chemical_Formula
  • C13H16ClNO.HCl
Legacy_Concept_Name
  • Ketamine_Hydrochloride
CHEBI_ID
  • CHEBI:650657
FULL_SYN
  • Ketamine HydrochloridePTNCI
  • Ketamine HClSYNCI
  • KETAMINE HYDROCHLORIDEPTFDAO18YUO0I83
  • KetalarPTNCI-GLOSSCDR0000589408
  • KetalarBRNCI
  • ketamine hydrochloridePTNCI-GLOSSCDR0000589409
DEFINITION
  • The hydrochloride salt of a synthetic derivative of cyclohexanone with analgesic and anesthetic activities. Although its mechanism of action is not well understood, ketamine appears to non-competitively block N-methyl-D-aspartate (NMDA) receptors and may interact with opioid mu receptors and sigma receptors, thereby reducing pain perception, inducing sedation, and producing dissociative anesthesia.NCI
code
  • C29142
sameAs
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