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AttributesValues
rdf:type
rdfs:label
  • Fluvoxamine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Fluvoxamine
UMLS_CUI
  • C0085228
CAS_Registry
  • 54739-18-3
FDA_UNII_Code
  • O4L1XPO44W
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat obsessive-compulsive disorder. It is a type of antidepressant agent and selective serotonin reuptake inhibitor (SSRI).NCI-GLOSS
Chemical_Formula
  • C15H21F3N2O2
Legacy_Concept_Name
  • Fluvoxamine
CHEBI_ID
  • CHEBI:5138
FULL_SYN
  • FluvoxaminePTNCI
  • fluvoxaminePTNCI-GLOSSCDR0000450109
  • FLUVOXAMINEPTFDAO4L1XPO44W
DEFINITION
  • A 2-aminoethyl oxime ether of aralkylketones, with antidepressant, antiobsessive-compulsive, and anxiolytic properties. Fluvoxamine, chemically unrelated to other selective serotonin reuptake inhibitors, selectively blocks serotonin reuptake by inhibiting the serotonin reuptake pump at the presynaptic neuronal membrane. This increases serotonin levels within the synaptic cleft, prolongs serotonergic transmission and decreased serotonin turnover, thereby leading to antidepressant, anxiolytic and antiobsessive-compulsive effects. Fluvoxamine shows no significant affinity for histaminergic, alpha or beta adrenergic, muscarinic, or dopaminergic receptors in vitro.NCI
code
  • C61769
sameAs
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