About: Selective Serotonin Reuptake Inhibitor

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Attributes	Values
rdf:type	Class
rdfs:label	Selective Serotonin Reuptake Inhibitor
rdfs:subClassOf	Agent Affecting Nervous System
Semantic_Type	Chemical Viewed Functionally
Preferred_Name	Selective Serotonin Reuptake Inhibitor
UMLS_CUI	C0360105
ALT_DEFINITION	A type of drug that is used to treat depression. Selective serotonin reuptake inhibitors slow the process by which serotonin (a substance that nerves use to send messages to one another) is reused by nerve cells that make it. This increases the amount of serotonin available for stimulating other nerves.NCI-GLOSS
CHEBI_ID	CHEBI:50949
FULL_SYN	SSRIPTNCI-GLOSSCDR0000335509 selective serotonin reuptake inhibitorPTNCI-GLOSSCDR0000335507 Selective Serotonin Reuptake InhibitorPTNCI
DEFINITION	Any agent that increases the extracellular level of the neurotransmitter serotonin (5-HT) by inhibiting its reuptake into the presynaptic cell. Increased level in the synaptic cleft prolongs the action of 5-HT on the postsynaptic receptor. This type of agent is typically used as an antidepressant and in the treatment of anxiety disorders and some personality disorders. They are also typically effective and used in treating some cases of insomnia.NCI
code	C94725
is rdfs:subClassOf of	SERTRALINE HYDROCHLORIDE SERTRALINE Lometraline Lometraline Hydrochloride Pirandamine PAROXETINE HYDROCHLORIDE FLUOXETINE HYDROCHLORIDE CITALOPRAM HYDROBROMIDE Fluvoxamine Maleate ESCITALOPRAM OXALATE Paroxetine Mesylate FLUOXETINE CITALOPRAM ESCITALOPRAM FLUVOXAMINE Fluoxetine Hydrochloride, (R)- PAROXETINE Pirandamine Hydrochloride Dapoxetine Dapoxetine Hydrochloride Paroxetine Hydrochloride Hemihydrate Indatraline

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