About: Demeclocycline     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Demeclocycline
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Demeclocycline
UMLS_CUI
  • C0011276
CAS_Registry
  • 127-33-3
FDA_UNII_Code
  • 5R5W9ICI6O
Contributing_Source
  • FDA
Chemical_Formula
  • C21H21ClN2O8
Legacy_Concept_Name
  • Demeclocycline
CHEBI_ID
  • CHEBI:4392
FULL_SYN
  • DEMECLOCYCLINEPTFDA5R5W9ICI6O
  • 7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamideSNNCI
  • DemeclocyclinePTNCI
DEFINITION
  • A semi-synthetic, broad-spectrum naphthacene antibiotic produced by the bacterium Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S ribosomal subunit and prevents binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. Demeclocycline also inhibits the effect of vasopressin on the renal tubules, thereby causing diuresis.NCI
code
  • C47980
sameAs
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