About: Acyclovir Sodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Acyclovir Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Acyclovir Sodium
UMLS_CUI
  • C0592290
CAS_Registry
  • 69657-51-8
FDA_UNII_Code
  • 927L42J563
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 531923
PDQ_Closed_Trial_Search_ID
  • 531923
Chemical_Formula
  • C8H10N5O3.Na
Legacy_Concept_Name
  • Acyclovir_Sodium
FULL_SYN
  • ACYCLOVIR SODIUMPTFDA927L42J563
  • Acyclovir SodiumPTNCI
  • 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one Momsodium SaltSNNCI
  • 9-((2-Hydroxyethoxy)methyl)guanine Monosodium SaltSNNCI
  • Zovirax for InjectionBRNCI
DEFINITION
  • The sodium salt form of acyclovir, a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family. After conversion in vivo to the active metabolite acyclovir triphosphate by viral thymidine kinase, acyclovir competitively inhibits viral DNA polymerase by incorporating into the growing viral DNA chain and terminating further polymerization.NCI
code
  • C47956
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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