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AttributesValues
rdf:type
rdfs:label
  • Acyclovir
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name
  • Acyclovir
NSC_Code
  • 335752
  • 645011
UMLS_CUI
  • C0001367
CAS_Registry
  • 59277-89-3
FDA_UNII_Code
  • X4HES1O11F
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance used to prevent or treat cytomegalovirus and herpes simplex infections that may occur when the body is immunosuppressed. It belongs to the family of drugs called antivirals.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39134
PDQ_Closed_Trial_Search_ID
  • 39134
Chemical_Formula
  • C8H11N5O3
Legacy_Concept_Name
  • Acyclovir
CHEBI_ID
  • CHEBI:2453
FULL_SYN
  • 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-oneSNNCI
  • 9-[(2-Hydroxyethoxy)methyl]guanineSNNCI
  • Wellcome-248UCNNCI
  • 9-[(2-Hydroxyethoxy)-methyl]guanineSYDTPNSC0645011
  • ACVABNCI
  • AcycloguanosineSYNCI
  • AcycloguanosineSYDTPNSC0645011
  • ACYCLOVIRPTFDAX4HES1O11F
  • BW-248UCNNCI
  • AclovirFBNCI
  • ViroraxFBNCI
  • ZoviraxBRNCI
  • CargosilFBNCI
  • AciclovirSYNCI
  • AcyclovirPTNCI
  • acyclovirPTNCI-GLOSSCDR0000045167
  • AcicloftalFBNCI
DEFINITION
  • A synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family. After conversion in vivo to the active metabolite acyclovir triphosphate by viral thymidine kinase, acyclovir competitively inhibits viral DNA polymerase by incorporating into the growing viral DNA chain and terminating further polymerization.NCI
code
  • C205
sameAs
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