About: Recombinant Colony Stimulating Factor

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Attributes	Values
rdf:type	Class
rdfs:label	Recombinant Colony Stimulating Factor
rdfs:subClassOf	Recombinant Cytokine Recombinant Hematopoietic Growth Factor
Semantic_Type	Amino Acid, Peptide, or Protein Pharmacologic Substance
Preferred_Name	Recombinant Colony Stimulating Factor
UMLS_CUI	C0376561
Legacy_Concept_Name	Therapeutic_Colony_Stimulating_Factor
FULL_SYN	CSFABNCI Recombinant Colony Stimulating FactorPTNCI Recombinant Hematopoietic Colony-stimulating FactorSYNCI
DEFINITION	Glycoprotein growth factors produced by monocytes, macrophages, or activated lymphocytes that stimulate the proliferation of bone marrow cells and differentiation of stem cells into colonies of granulocytes, monocytes, or macrophages. These substances act in either paracrine or autocrine fashion on marrow cells, appear to act synergistically in complex and poorly understood ways. Each appears to exert actions on several lines of progenitor cells and to influence end cell function. Treatment with colony-stimulating factors (CSF) can help the blood-forming tissue recover from the effects of chemotherapy and radiation therapy. These factors include interleukin-3 (IL-3), granulocyte colony-stimulating factor (G-CSF), macrophage colony-stimulating factor (M-CSF), and granulocyte-macrophage colony-stimulating factor (GM-CSF).NCI
code	C387
is rdf:first of	nodeID://b733376 nodeID://b733377 nodeID://b733378 nodeID://b733379 nodeID://b733380
is rdfs:subClassOf of	Lipegfilgrastim Recombinant Dimeric Filgrastim Fusion Protein F627 Leridistim Pegylated Granulocyte Colony Stimulating Factor MAXY-G34 Recombinant Human Albumin-Human Granulocyte Colony-Stimulating Factor Pegfilgrastim Biosimilar LA-EP2006 Macrophage Colony-Stimulating Factor FILGRASTIM Pegfilgrastim Promegapoietin ROMIPLOSTIM Recombinant Human Thrombopoietin Y-shape Branched Pegylated Filgrastim

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