About: Fluoxetine Hydrochloride

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Fluoxetine Hydrochloride
rdfs:subClassOf	ANTIDEPRESSANTS Selective Serotonin Reuptake Inhibitor
Has_Free_Acid_Or_Base_Form	FLUOXETINE
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Pharmacologic Substance
Preferred_Name	Fluoxetine Hydrochloride
NSC_Code	714457
UMLS_CUI	C0733380
CAS_Registry	59333-67-4
FDA_UNII_Code	I9W7N6B1KJ
Contributing_Source	FDA
Chemical_Formula	C17H18F3NO.HCl
Legacy_Concept_Name	Fluoxetine_Hydrochloride
FULL_SYN	Fluoxetine HydrochloridePTNCI ProzacSYDTPNSC0714457 FLUOXETINE HYDROCHLORIDEPTFDAI9W7N6B1KJ ProzacBRNCI
DEFINITION	The hydrochloride salt form of fluoxetine, a diphenhydramine derivative and selective serotonin reuptake inhibitor with antidepressant, antiobsessional and antibulimic effects. Fluoxetine binds to the presynaptic serotonin receptor resulting in negative allosteric modulation of the receptor complex, thereby blocking recycling of serotonin by the presynaptic receptor. Inhibition of serotonin reuptake by fluoxetine enhances serotonergic function through serotonin accumulation in the synaptic space, resulting in long-term desensitization and downregulation of 5HT1 (serotonin) receptors leading to antidepressant, antiobsessional and antibulimic effects via various nerve pathways in the brain.NCI
code	C2829
sameAs	FLUOXETINE HYDROCHLORIDE FLUOXETINE HYDROCHLORIDE
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0351280
is Has_Salt_Form of	FLUOXETINE
is sameAs of	FLUOXETINE HYDROCHLORIDE FLUOXETINE HYDROCHLORIDE FLUOXETINE HYDROCHLORIDE

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