About: Mutated Ras Peptide     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Mutated Ras Peptide
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Mutated Ras Peptide
UMLS_CUI
  • C1513777
Legacy_Concept_Name
  • Mutated_Ras_Peptide
FULL_SYN
  • Ras Peptides (mutated)SYNCI
  • Mutated Ras PeptidePTNCI
DEFINITION
  • Point-mutation products of Ras proto-oncogene are found to associated with a broad spectrum of human carcinomas. Mutation locations are notably at codons 12, 13, and 61. Codon 12 mutations form more than 90% of all Ras mutations in human cancers. Degraded Ras peptides have been shown to stimulate immunogenic response. Various forms of mutated Ras peptides-adjuvant are used as vaccine along with cytokines that could potentially enhance the body's immunological response in many neoplastic conditions. (NCI04)NCI
code
  • C2730
is rdfs:subClassOf of
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