About: Recombinant Fowlpox-TRICOM Vaccine

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Attributes	Values
rdf:type	Class
rdfs:label	Recombinant Fowlpox-TRICOM Vaccine
rdfs:subClassOf	Fowlpox Virus Vaccine nodeID://b674594 nodeID://b674595 nodeID://b674596 nodeID://b674597
Semantic_Type	Pharmacologic Substance Virus
Preferred_Name	Recombinant Fowlpox-TRICOM Vaccine
NSC_Code	710658
UMLS_CUI	C1134570
In_Clinical_Trial_For	Metastatic Solid Tumors and Advanced Squamous Cell Carcinoma of the Oral Cavity; or Oropharynx; or Nodal; or Dermal Metastasis.
ALT_DEFINITION	A cancer vaccine made with a form of a chicken virus that does not cause disease in humans. It is being studied in the treatment of some types of cancer. The virus is changed in the laboratory to make human proteins that may help immune cells in the body kill tumor cells.NCI-GLOSS
PDQ_Open_Trial_Search_ID	38543
PDQ_Closed_Trial_Search_ID	38543
Legacy_Concept_Name	Fowlpox-TRICOM_Vaccine
FULL_SYN	rF-TRICOM (B7.1.iCAM1-LFA3-Fowlpox)SYNCI Recombinant Fowlpox-TRICOM VaccinePTNCI Recombinant Fowlpox-TRICOMSYNCI recombinant fowlpox-TRICOM vaccinePTNCI-GLOSSCDR0000543384 rF-TRICOMPTNCI-GLOSSCDR0000573127
DEFINITION	A vaccine comprised of a recombinant fowlpox virus vector encoding a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM), which may enhance antigen presentation and activate cytotoxic T-cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells. (NCI04)NCI
code	C2667
is rdfs:subClassOf of	Falimarev rF-PSA/PSMA/TRICOM Recombinant Fowlpox-CEA(6D)/TRICOM Vaccine Recombinant Fowlpox-PSA(L155)/TRICOM Vaccine Fowlpox-PSA-TRICOM Vaccine
is someValuesFrom of	nodeID://b674593

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