About: Recombinant Fowlpox-CEA(6D)/TRICOM Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Recombinant Fowlpox-CEA(6D)/TRICOM Vaccine
rdfs:subClassOf
Has_Target
Semantic_Type
  • Pharmacologic Substance
  • Virus
Preferred_Name
  • Recombinant Fowlpox-CEA(6D)/TRICOM Vaccine
NSC_Code
  • 710068
UMLS_CUI
  • C0935790
In_Clinical_Trial_For
  • high risk beast cancer; locally recurrent or metastatic malignancies expressing CEA; advanced or metastatic CEA-expressing adenocarcinomas; previously untreated metastatic breast cancer.
PDQ_Open_Trial_Search_ID
  • 38216
PDQ_Closed_Trial_Search_ID
  • 38216
Legacy_Concept_Name
  • Fowlpox-CEA-TRICOM_Vaccine
FULL_SYN
  • rF-CEA(6D)TRICOMSYNCI
  • Recombinant Fowlpox-CEA-TRICOM VaccineSYNCI
  • fowlpox-CEA-B7.1/ICAM-1/LFA-3SYNCI
  • Recombinant Fowlpox-CEA(6D)/TRICOM VaccinePTNCI
DEFINITION
  • A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the carcinoembryonic antigen (CEA) and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM). This agent may enhance CEA presentation to antigen presenting cells (APC) and activate cytotoxic T-cells against CEA-expressing tumors. (NCI04)NCI
code
  • C2620
is someValuesFrom of
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