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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Pixantrone
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Pixantrone
UMLS_CUI
  • C0253355
CAS_Registry
  • 144510-96-3
FDA_UNII_Code
  • F5SXN2KNMR
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called antitumor antibiotics.NCI-GLOSS
Chemical_Formula
  • C17H19N5O2
Legacy_Concept_Name
  • Pixantrone
FULL_SYN
  • pixantronePTNCI-GLOSSCDR0000322231
  • 6,9-Bis((2-aminoethyl)amino)benzo(g)isoquinoline-5,10-dioneSNNCI
  • PIXANTRONEPTFDAF5SXN2KNMR
  • PixantronePTNCI
DEFINITION
  • A synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity.NCI
code
  • C26663
http://linked.open...y/mesh/hasConcept
is someValuesFrom of
is Has_Free_Acid_Or_Base_Form of
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