About: Aminopterin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Aminopterin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Aminopterin
NSC_Code
  • 739
UMLS_CUI
  • C0002583
CAS_Registry
  • 54-62-6
FDA_UNII_Code
  • JYB41CTM2Q
Contributing_Source
  • FDA
ALT_DEFINITION
  • An anticancer drug that belongs to the family of drugs called antimetabolites.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39141
PDQ_Closed_Trial_Search_ID
  • 39141
Chemical_Formula
  • C19H20N8O5
Legacy_Concept_Name
  • Aminopterin
CHEBI_ID
  • CHEBI:22526
FULL_SYN
  • APGASYDTPNSC0000739
  • AminopterinSYDTPNSC0000739
  • 4-Amino-PGASYNCI
  • AminopterinPTNCI
  • 4-Aminopteroylglutamic acidSYDTPNSC0000739
  • aminopterinPTNCI-GLOSSCDR0000045171
  • Aminopteroylglutamic AcidSYNCI
  • AminopterinPTDCP02633
  • APGAABNCI
  • 4-Aminopteroylglutamic AcidSYNCI
  • 4-Aminofolic AcidSYNCI
  • 4-Aminofolic acidSYDTPNSC0000739
  • AMINOPTERINPTFDAJYB41CTM2Q
DEFINITION
  • A synthetic derivative of pterins with antineoplastic and immunosuppressive properties. As a folate analogue, aminopterin competes for the folate binding site of the enzyme dihydrofolate reductase, thereby blocking tetrahydrofolate synthesis, and resulting in depletion of nucleotide precursors and inhibition of DNA, RNA and protein synthesis. (NCI04)NCI
code
  • C235
sameAs
http://linked.open...y/mesh/hasConcept
is someValuesFrom of
is Has_Free_Acid_Or_Base_Form of
is sameAs of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 18 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software