About: Vincristine Liposomal     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Vincristine Liposomal
rdfs:subClassOf
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Vincristine Liposomal
UMLS_CUI
  • C1519991
Legacy_Concept_Name
  • Vincristine_Liposomal
FULL_SYN
  • Vincristine, LiposomalSYNCI
  • Onco TCSBRNCI
  • Lipid-Encapsulated VincristineSYNCI
  • Vincristine LiposomeSYNCI
  • VincaXomeBRNCI
  • VincacineSYNCI
  • Liposomal VincristineSYNCI
  • Vincristine LiposomalPTNCI
DEFINITION
  • A liposomal formulation of Vincristine designed to reduce toxicity and improve efficacy. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the cell cycle and interferes with the formation of the mitotic spindle, thereby arresting tumor cells in metaphase. This agent also depolymerizes microtubules and may also interfere with amino acid, cyclic AMP, and glutathione metabolism; calmodulin-dependent Ca++ -transport ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis. (NCI)NCI
code
  • C2104
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 18 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software