About: Sp1 Activation Cofactor Gene     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Sp1 Activation Cofactor Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • Sp1 Activation Cofactor Gene
UMLS_CUI
  • C1336035
Legacy_Concept_Name
  • Sp1_Activation_Cofactor_Gene
FULL_SYN
  • Sp1 Activation Cofactor GenePTNCI
Gene_Encodes_Product
  • Cofactor Required for SP1 Activation
DEFINITION
  • Sp1 Activation Cofactor Genes encode (at least 9) protein subunits of the CRSP (Cofactor Required for SP1 activation) complex, which, along with TFIID, is required for efficient activation of gene transcription by SP1, a transcription factor that recognizes enhancer sites in target DNA. Many CRSP complex proteins are also components of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins that interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. (NCI)NCI
code
  • C20686
is rdfs:subClassOf of
is someValuesFrom of
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