About: Mediator Complex Component Gene     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Mediator Complex Component Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • Mediator Complex Component Gene
UMLS_CUI
  • C1334684
Legacy_Concept_Name
  • Mediator_Complex_Component_Gene
FULL_SYN
  • Mediator Complex Component GenePTNCI
DEFINITION
  • Regulation of mRNA synthesis requires intermediary proteins that transduce regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Mediator Complex Component Genes encode the mediator complex, one type of intermediary and which consists of approximately 20 polypeptides. It is physically associated with RNA polymerase II and is essential for transcriptional activation. (from OMIM 602984)NCI
code
  • C20658
is rdfs:subClassOf of
is someValuesFrom of
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