About: Depsipeptide Antineoplastic Antibiotic     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Depsipeptide Antineoplastic Antibiotic
rdfs:subClassOf
Semantic_Type
  • Chemical Viewed Functionally
Preferred_Name
  • Depsipeptide Antineoplastic Antibiotic
UMLS_CUI
  • C0796678
Legacy_Concept_Name
  • Depsipeptide_Antibiotic
FULL_SYN
  • DepsipeptideSYNCI
  • Depsipeptide Antineoplastic AntibioticPTNCI
DEFINITION
  • A bicyclic peptide antibiotic with one or more amide bonds replaced by ester bonds. Depsipeptide antibiotics act as histone deacetylase inhibitors and regulate chromatin structure and transcription by increasing histone acetylation, thereby resulting in alterations in gene expression and inducing cell differentiation, cell cycle arrest, and apoptosis.NCI
code
  • C1976
sameAs
http://linked.open...y/mesh/hasConcept
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is rdfs:subClassOf of
is sameAs of
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