About: Recombinant Interferon Alfa-2a

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About: Recombinant Interferon Alfa-2a Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Recombinant Interferon Alfa-2a
rdfs:subClassOf	Recombinant Interferon Alfa nodeID://b683305 nodeID://b683306 nodeID://b683307 nodeID://b683308 nodeID://b683309
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Amino Acid, Peptide, or Protein Pharmacologic Substance
Preferred_Name	Recombinant Interferon Alfa-2a
NSC_Code	367982
UMLS_CUI	C0021734
CAS_Registry	76543-88-9
Accepted_Therapeutic_Use_For	Chronic phase Philadelphia chromosome-positive chronic myelogenous leukemia; hairy cell leukemia; chronic hepatitis C; AIDs-related Kaposis sarcoma; bladder; ovarian; cervical cancer; non-Hodgkins lymphoma; renal cell carcinoma; melanoma.
In_Clinical_Trial_For	T-cell lymphoma; mycosis fungoides; hematologic neoplasms.
FDA_UNII_Code	47RRR83SK7
Contributing_Source	FDA
PDQ_Open_Trial_Search_ID	467189
PDQ_Closed_Trial_Search_ID	467189
Legacy_Concept_Name	Interferon_Alpha-2a
FULL_SYN	IFN-Alpha 2SYNCI rHuIFN-a 2aABNCI IFN alpha-2ASYNCI Alpha 2 InterferonSYNCI Interferon alfa 2aSYNCI INTERFERON ALFA-2APTFDA47RRR83SK7 Recombinant Interferon Alfa-2aPTNCI Roferon ABRNCI Roceron-AFBNCI Recombinant Interferon Alpha-2aSYNCI LaroferonFBNCI
DEFINITION	A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell-surface receptor, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune modulating effects. (NCI04)NCI
code	C1952
sameAs	INTERFERON ALFA-2A
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0023693
is sameAs of	INTERFERON ALFA-2A INTERFERON ALFA-2A INTERFERON ALFA-2A

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