About: Recombinant Interferon Alfa

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Recombinant Interferon Alfa Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Recombinant Interferon Alfa
rdfs:subClassOf	Angiogenesis Activator Inhibitor Recombinant Interferon
Semantic_Type	Amino Acid, Peptide, or Protein Pharmacologic Substance
Preferred_Name	Recombinant Interferon Alfa
UMLS_CUI	C1622507
Accepted_Therapeutic_Use_For	See specific agents.
In_Clinical_Trial_For	See specific agents.
PDQ_Open_Trial_Search_ID	40467
PDQ_Closed_Trial_Search_ID	40467
Legacy_Concept_Name	Therapeutic_Interferon_Alfa
FULL_SYN	Interferon AlfaSYNCI Lymphoblast InterferonSYNCI Lymphoblastoid InterferonSYNCI Alpha InterferonSYNCI alpha-InterferonSYNCI Recombinant Interferon AlfaPTNCI AlferonBRNCI Interferon AlfaPTDCP20108 Leukocyte InterferonSYNCI
DEFINITION	A class of naturally-isolated or recombinant therapeutic peptides used as antiviral and anti-tumor agents. Alpha interferons are cytokines produced by nucleated cells (predominantly natural killer (NK) leukocytes) upon exposure to live or inactivated virus, double-stranded RNA or bacterial products. These agents bind to specific cell-surface receptors, resulting in the transcription and translation of genes containing an interferon-specific response element. The proteins so produced mediate many complex effects, including antiviral effects (viral protein synthesis); antiproliferative effects (cellular growth inhibition and alteration of cellular differentiation); anticancer effects (interference with oncogene expression); and immune-modulating effects (natural killer cell activation, alteration of cell surface antigen expression, and augmentation of lymphocyte and macrophage cytotoxicity). (NCI04)NCI
code	C225
is rdfs:subClassOf of	INTERFERON ALFACON-1 INTERFERON ALFA-2A Interferon Alfa-N1 INTERFERON ALFA-3N Recombinant Interferon Alfa-1b Natural IFN-alpha OPC-18 Recombinant Interferon Alpha 2b-like Protein Multi-subtype Natural Human Leukocyte Interferon Alpha INTERFERON ALFA-2B Pegylated Interferon Alfa Albinterferon Alfa-2b
is someValuesFrom of	nodeID://b644921 nodeID://b647443 nodeID://b647701 nodeID://b648292 nodeID://b650351 nodeID://b650772 nodeID://b651057 nodeID://b651906 nodeID://b651931 nodeID://b652767 nodeID://b656772 nodeID://b656780 nodeID://b656880 nodeID://b657065 nodeID://b657209 nodeID://b657512 nodeID://b657518 nodeID://b657595 nodeID://b657608 nodeID://b657675 nodeID://b657696 nodeID://b657705 nodeID://b657707 nodeID://b658912 nodeID://b659730 nodeID://b659863 nodeID://b659865 nodeID://b659869 nodeID://b659875 nodeID://b659879 nodeID://b659885 nodeID://b660145 nodeID://b660169 nodeID://b660293 nodeID://b660295 nodeID://b660426 nodeID://b660430 nodeID://b660434 nodeID://b660437 nodeID://b662912 nodeID://b663007 nodeID://b663467 nodeID://b663469 nodeID://b663474 nodeID://b663479 nodeID://b663481 nodeID://b663731 nodeID://b664261 nodeID://b664275 nodeID://b664298 nodeID://b665931 nodeID://b665934 nodeID://b666445 nodeID://b666562 nodeID://b667580 nodeID://b667582 nodeID://b667731 nodeID://b669883 nodeID://b669904 nodeID://b671095 nodeID://b673553 nodeID://b673558 nodeID://b673570 nodeID://b673693 nodeID://b673707

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 18 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software