About: T-Cell Differentiation

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	T-Cell Differentiation
rdfs:subClassOf	Cell Differentiation Process nodeID://b716626 nodeID://b716627 nodeID://b716628
Semantic_Type	Cell Function
Preferred_Name	T-Cell Differentiation
UMLS_CUI	C1155013
Legacy_Concept_Name	T-Cell_Development
FULL_SYN	T-Cell DifferentiationPTNCI T-Lymphocyte DevelopmentSYNCI T-Cell OntogenySYNCI T-Cell DevelopmentSYNCI
DEFINITION	Development of bone marrow-derived stem cells in the thymus through stages of positive selection under the influence of epithelial cells in the thymic cortex and negative selection under the influence of bone marrow-derived dendritic cells at the corticomedullary junction. Thymic T cell precursors (thymocytes) progress through phases expressing both CD4 and CD8 coreceptors to a single positive stage expressing only CD4 or CD8 in addition to the T cell receptor. They are then allowed to leave the thymus and enter the periphery via the lymphatics or venules of the circulatory system as mature T cells. (NCI/OSP)NCI
code	C19055
is rdfs:subClassOf of	T-Cell Differentiation in the Thymus
is someValuesFrom of	nodeID://b643331 nodeID://b647498 nodeID://b653557 nodeID://b656528 nodeID://b671806 nodeID://b673153 nodeID://b681713 nodeID://b683990 nodeID://b685768 nodeID://b687683 nodeID://b695362 nodeID://b697244 nodeID://b697722 nodeID://b706549 nodeID://b706579 nodeID://b716629

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