About: Warfarin Sodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Warfarin Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Warfarin Sodium
UMLS_CUI
  • C0699129
CAS_Registry
  • 129-06-6
FDA_UNII_Code
  • 6153CWM0CL
Contributing_Source
  • FDA
Chemical_Formula
  • C19H15O4.Na
Legacy_Concept_Name
  • Warfarin_Sodium
CHEBI_ID
  • CHEBI:10034
FULL_SYN
  • ProthromadinSYDTPNSC0059813
  • ProthromadinSYNCI
  • WARFARIN SODIUMPTFDA6153CWM0CL
  • Warfarin SodiumPTNCI
  • WaranFBNCI
  • CoumadinSYDTPNSC0059813
  • MarevanFBNCI
  • PanwarfinSYDTPNSC0059813
  • CoumadinBRNCI
  • WarfiloneFBNCI
  • PanwarfinBRNCI
  • TintoraneSYNCI
DEFINITION
  • The sodium salt form of warfarin, a coumarin and a vitamin K antagonist, with anticoagulant activity. Warfarin sodium inhibits both vitamin K and vitamin K epoxide reductases, thereby interfering with the cyclic interconversion of vitamin K epoxide to its reduced form, vitamin KH2. Vitamin KH2 is a cofactor for the carboxylation of glutamate residues on the N-terminal regions of vitamin K-dependent proteins. As a result, maturation of vitamin K-dependent coagulation factors II, VII, IX, and X and anticoagulant proteins C and S is inhibited. Without these coagulation factors, thrombogenesis and blood clot formation are prevented.NCI
code
  • C1658
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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