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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Losoxantrone
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Losoxantrone
NSC_Code
  • 357885
UMLS_CUI
  • C0245032
CAS_Registry
  • 88303-60-0
FDA_UNII_Code
  • 47KPH00809
Contributing_Source
  • FDA
ALT_DEFINITION
  • An anticancer drug that belongs to the family of drugs called antipyrazoles.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 41809
PDQ_Closed_Trial_Search_ID
  • 41809
Chemical_Formula
  • C22H27N5O4
Legacy_Concept_Name
  • Losoxantrone
FULL_SYN
  • BiantrazoleSYDTPNSC0357885
  • LOSOXANTRONEPTFDA47KPH00809
  • BiantrazoleSYNCI
  • LosoxantronePTNCI
  • CI-941SYDTPNSC0357885
  • losoxantronePTNCI-GLOSSCDR0000045401
  • CI-941CNNCI
  • DuP 941CNNCI
DEFINITION
  • An anthrapyrazole-based antineoplastic antibiotic. Losoxantrone intercalates into DNA, induces single- and double-stranded DNA breaks and inhibits topoisomerase II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis. Losoxantrone is less cardiotoxic than doxorubicin.NCI
code
  • C1521
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