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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Sumatriptan
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Sumatriptan
UMLS_CUI
  • C0075632
CAS_Registry
  • 103628-46-2
FDA_UNII_Code
  • 8R78F6L9VO
Contributing_Source
  • FDA
ALT_DEFINITION
  • A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of migraines.MSH2002_06_01
Chemical_Formula
  • C14H21N3O2S
Legacy_Concept_Name
  • Sumatriptan
CHEBI_ID
  • CHEBI:10650
FULL_SYN
  • SumatriptanPTNCI
  • SUMATRIPTANPTFDA8R78F6L9VO
DEFINITION
  • A sulfonamide triptan with vasoconstrictor activity. Sumatriptan selectively binds to and activates serotonin 5-HT1D receptors in the central nervous system (CNS), thereby constricting cerebral blood vessels. This may lead to a relief in pain from vascular headaches. Sumatriptan may also relieve vascular headaches by decreasing the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater during a migraine, by reducing extravasation of plasma proteins, and by decreasing the release of other mediators of inflammation from the trigeminal nerve.NCI
code
  • C1240
sameAs
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