About: EGFR Inhibitor HM61713     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • EGFR Inhibitor HM61713
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • EGFR Inhibitor HM61713
NCI_META_CUI
  • CL435909
PDQ_Open_Trial_Search_ID
  • 733621
PDQ_Closed_Trial_Search_ID
  • 733621
FULL_SYN
  • HM61713CNNCI
  • EGFR Inhibitor HM61713PTNCI
DEFINITION
  • An orally available small molecule, mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. EGFR inhibitor HM61713 binds to and inhibits mutant forms of EGFR, thereby leading to cell death of EGFR-expressing tumor cells. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced as compared to non-selective EGFR inhibitors which also inhibit the EGFR wild type form.NCI
code
  • C101791
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