About: Fleroxacin

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase. (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...ugbank/indication	Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. (en)
sameAs	Fleroxacin Fleroxacin
Title	Fleroxacin (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB04576/identifier/drugbank/DB04576 http://linked.opendata.cz/resource/drugbank/drug/DB04576/identifier/kegg-compound/C13179 http://linked.opendata.cz/resource/drugbank/drug/DB04576/identifier/kegg-drug/D01716 http://linked.opendata.cz/resource/drugbank/drug/DB04576/identifier/pharmgkb/PA164774762 http://linked.opendata.cz/resource/drugbank/drug/DB04576/identifier/wikipedia/Fleroxacin
http://linked.open...mechanismOfAction	The inhibition of DNA gyrase and DNA topoisomerase 2 leads ultimately to cell death as these enzymes are required for bacterial DNA replication, transcription, repair, strand supercoiling repair, and recombination. (en)
http://linked.open.../drugbank/synonym	Fleroxacin (en) FLRX (en) Fleroxacine (en) Fleroxicin (en) Megalocin (en) Megalocin (TN) (en) Megalone (en) Megalone (TN) (en) Megalosin (en) Quinodis (en) Fleroxacino (en) Fleroxacinum (en)
http://linked.open.../drug/hasAHFSCode	http://linked.opendata.cz/resource/AHFS/52-04-04 http://linked.opendata.cz/resource/AHFS/8-12-18
http://linked.open...k/foodInteraction	Avoid excessive coffee or tea (caffeine) (en) Take with a full glass of water (en) Take without regard to meals (en) Avoid milk, calcium containing dairy products, iron, magnesium, zinc, antacids, or aluminum salts 2 hours before or 6 hours after using antacids while on this medication. (en)
http://linked.open...ynthesisReference	"DrugSyn.org":http://www.drugsyn.org/Fleroxacin.htm (en)
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0025289
http://linked.open...ogy/drugbank/logP	http://linked.opendata.cz/resource/drugbank/property/271B3FF6-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Fleroxacin
http://linked.open...ugbank/absorption	Rapidly and well absorbed from the gastrointestinal tract after oral administration. (en)
http://linked.open...aco2-Permeability	http://linked.opendata.cz/resource/drugbank/property/271B3FF7-363D-11E5-9242-09173F13E4C5
http://linked.open...casRegistryNumber	79660-72-3 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...ank/Melting-Point	http://linked.opendata.cz/resource/drugbank/property/271B3FF5-363D-11E5-9242-09173F13E4C5

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