About: Fleroxacin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
http://linked.open...gbank/description
  • Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase. (en)
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...ugbank/indication
  • Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. (en)
sameAs
Title
  • Fleroxacin (en)
adms:identifier
http://linked.open...mechanismOfAction
  • The inhibition of DNA gyrase and DNA topoisomerase 2 leads ultimately to cell death as these enzymes are required for bacterial DNA replication, transcription, repair, strand supercoiling repair, and recombination. (en)
http://linked.open.../drugbank/synonym
  • Fleroxacin (en)
  • FLRX (en)
  • Fleroxacine (en)
  • Fleroxicin (en)
  • Megalocin (en)
  • Megalocin (TN) (en)
  • Megalone (en)
  • Megalone (TN) (en)
  • Megalosin (en)
  • Quinodis (en)
  • Fleroxacino (en)
  • Fleroxacinum (en)
http://linked.open.../drug/hasAHFSCode
http://linked.open...k/foodInteraction
  • Avoid excessive coffee or tea (caffeine) (en)
  • Take with a full glass of water (en)
  • Take without regard to meals (en)
  • Avoid milk, calcium containing dairy products, iron, magnesium, zinc, antacids, or aluminum salts 2 hours before or 6 hours after using antacids while on this medication. (en)
http://linked.open...ynthesisReference
  • "DrugSyn.org":http://www.drugsyn.org/Fleroxacin.htm (en)
http://linked.open...y/mesh/hasConcept
http://linked.open...ogy/drugbank/logP
http://linked.open...l/drug/hasATCCode
http://linked.open...ugbank/absorption
  • Rapidly and well absorbed from the gastrointestinal tract after oral administration. (en)
http://linked.open...aco2-Permeability
http://linked.open...casRegistryNumber
  • 79660-72-3 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...ank/Melting-Point
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