About: Summarizing gene-expression-based classifiers by meta-mining comprehensible relational patterns

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Není k dispozici (cs) We propose a methodology for predictive classification from gene expression data, able to combine the robustness of high-dimensional statistical classification methods with the comprehensibility and interpretability of simple logic-based models. We first construct a robust classifier combining contributions of a large number of gene expression values, and then (meta)-mine the classifier for compact summarizations of subgroups among genes associated with a given class therein. The subgroups are described by means of relational logic features extracted from publicly available gene ontology information. The curse of dimensionality pertaining to the gene expression based classification problem due to the large number of attributes (genes) is turned into an advantage in the secondary, meta-mining task as here the original attributes become learning examples. We propose a methodology for predictive classification from gene expression data, able to combine the robustness of high-dimensional statistical classification methods with the comprehensibility and interpretability of simple logic-based models. We first construct a robust classifier combining contributions of a large number of gene expression values, and then (meta)-mine the classifier for compact summarizations of subgroups among genes associated with a given class therein. The subgroups are described by means of relational logic features extracted from publicly available gene ontology information. The curse of dimensionality pertaining to the gene expression based classification problem due to the large number of attributes (genes) is turned into an advantage in the secondary, meta-mining task as here the original attributes become learning examples. (en)
Title	Summarizing gene-expression-based classifiers by meta-mining comprehensible relational patterns Není k dispozici (cs) Summarizing gene-expression-based classifiers by meta-mining comprehensible relational patterns (en)
skos:prefLabel	Summarizing gene-expression-based classifiers by meta-mining comprehensible relational patterns Není k dispozici (cs) Summarizing gene-expression-based classifiers by meta-mining comprehensible relational patterns (en)
skos:notation	RIV/68407700:21230/06:03117834!RIV07-AV0-21230___
http://linked.open.../vavai/riv/strany	19 ; 24
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1ET101210513), P(KJB201210501), Z(MSM6840770012)
http://linked.open...vai/riv/dodaniDat	2007
http://linked.open...aciTvurceVysledku	Štěpánková, Olga Železný, Filip
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	České vysoké učení technické v Praze / Fakulta elektrotechnická
http://linked.open...dnocenehoVysledku	502464
http://linked.open...ai/riv/idVysledku	RIV/68407700:21230/06:03117834
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	acute lymphoblastic leukemia; acute myeloid leukemia; gene-expression-based classifiers; methodology for predictive (en)
http://linked.open.../riv/klicoveSlovo	acute lymphoblastic leukemia acute myeloid leukemia gene-expression-based classifiers methodology for predictive
http://linked.open...ontrolniKodProRIV	[88E6BC1E9F67]
http://linked.open...v/mistoKonaniAkce	Innsbruck
http://linked.open...i/riv/mistoVydani	Zürich
http://linked.open...i/riv/nazevZdroje	Proceedings of the Fourth IASTED International Conference on BIOMEDICAL ENGINEERING
http://linked.open...in/vavai/riv/obor	JC
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Relational machine learning for analysis of biomedical data Logic-based machine learning for genomic data analysis
http://linked.open...UplatneniVysledku	2006
http://linked.open...iv/tvurceVysledku	Lavrač, N. Tolar, J. Železný, Filip Štěpánková, Olga
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2006-02-15 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Transdisciplinární výzkum v oblasti biomedicínského inženýrství II
number of pages	6 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Acta Press
https://schema.org/isbn	0-88986-576-0
http://localhost/t...ganizacniJednotka	21230
is http://linked.open...avai/riv/vysledek of	Summarizing gene-expression-based classifiers by meta-mining comprehensible relational patterns Summarizing gene-expression-based classifiers by meta-mining comprehensible relational patterns

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