About: Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5     Goto   Sponge   NotDistinct   Permalink

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Description
  • Aktivace Wnt/beta-cateninové signální dráhy v myším embryonickém teleocephalonu reguluje expresi genu Sp5. Represorová aktivita domény R1 faktoru Sp5 je zprostředkována přímou interakcí s transkripčním korepresorem mSin3a. Transkripční faktor Sp5 převádí signál vedený do dráhy Wnt/beta-cateninu tím, že přímo reprimuje cílové geny Sp1. (cs)
  • The activation of Wnt/beta-catenin signaling in the embryonic mouse telencephalon results in the up-regulation of Sp5 gene. The repression activity of R1 domain of Sp5 is mediated through direct interaction with a transcriptional corepressor mSin3a. Sp5 transcription factor mediates the downstream responses to Wnt/beta-catenin signaling by directly repressing Sp1 target genes.
  • The activation of Wnt/beta-catenin signaling in the embryonic mouse telencephalon results in the up-regulation of Sp5 gene. The repression activity of R1 domain of Sp5 is mediated through direct interaction with a transcriptional corepressor mSin3a. Sp5 transcription factor mediates the downstream responses to Wnt/beta-catenin signaling by directly repressing Sp1 target genes. (en)
Title
  • Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5
  • Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5 (en)
  • Snížená regulace signálu Wnt cílových genů Sp1 transkripčním represorem Sp5 (cs)
skos:prefLabel
  • Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5
  • Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5 (en)
  • Snížená regulace signálu Wnt cílových genů Sp1 transkripčním represorem Sp5 (cs)
skos:notation
  • RIV/68378050:_____/07:00053521!RIV07-AV0-68378050
http://linked.open.../vavai/riv/strany
  • 1225;1237
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z50520514)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 461357
http://linked.open...ai/riv/idVysledku
  • RIV/68378050:_____/07:00053521
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Wnt-mediated signaling; Sp5 transcription factor; Sp1 target genes (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [5E4472C9EFB2]
http://linked.open...i/riv/nazevZdroje
  • Journal of Biological Chemistry
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 282
http://linked.open...iv/tvurceVysledku
  • Kozmik, Zbyněk
  • Scalabrin, S.
  • Vlček, Čestmír
  • Krauss, S.
  • Machoň, Ondřej
  • Fujimura, Naoko
  • Vacík, Tomáš
  • Diep, D.
  • Speth, M.
http://linked.open...n/vavai/riv/zamer
issn
  • 0021-9258
number of pages
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