About: Human papillomavirus (HPV) and HPV-associated tumour vaccines

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Human papillomaviruses were found to be closely associated with cervical cancer and some other anogenital carcinomas. Immunological intervention against high-risk HPV types can be done at the prophylactic and therapeutic levels. While prophylactic vaccines developed using HPV 16 E6/E7 oncoproteins are already being tested in clinical trials and show promising results, the problems connected with therapeutic vaccines developed using animal models have still to be resolved. Human papillomaviruses were found to be closely associated with cervical cancer and some other anogenital carcinomas. Immunological intervention against high-risk HPV types can be done at the prophylactic and therapeutic levels. While prophylactic vaccines developed using HPV 16 E6/E7 oncoproteins are already being tested in clinical trials and show promising results, the problems connected with therapeutic vaccines developed using animal models have still to be resolved. (en) Výzkum ukázal, že lidské papilomaviry jsou spojeny s rakovinou děložního čípku a řadou dalších anogenitálních karcinomů. Imunologický zásah proti vysoce rizikovým HPV lze provádět na profylaktické a terapeutické úrovni. Zatímco profylaktické vakcíny odvozené z HPV 16 E6/E7 onkoproteinů jsou již klinicky testovány se slibnými výsledky, problémy spojené s vývojem terapeutických vakcín na zvířatech je třeba ještě dořešit. (cs)
Title	Human papillomavirus (HPV) and HPV-associated tumour vaccines Human papillomavirus (HPV) and HPV-associated tumour vaccines (en) Lidský papilomavirus (HPV) a nádorové vakcíny odvozené od HPV (cs)
skos:prefLabel	Human papillomavirus (HPV) and HPV-associated tumour vaccines Human papillomavirus (HPV) and HPV-associated tumour vaccines (en) Lidský papilomavirus (HPV) a nádorové vakcíny odvozené od HPV (cs)
skos:notation	RIV/68378050:_____/06:00044807!RIV07-MZ0-68378050
http://linked.open.../vavai/riv/strany	45;46
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA301/04/0492), P(IAA500520605), P(NR7807), P(NR8004), Z(AV0Z50520514)
http://linked.open...iv/cisloPeriodika	1-2
http://linked.open...vai/riv/dodaniDat	2007
http://linked.open...aciTvurceVysledku	Bubeník, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	478404
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/06:00044807
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	HPV; tumour vaccines (en)
http://linked.open.../riv/klicoveSlovo	tumour vaccines HPV
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[D9F1EA6FBD94]
http://linked.open...i/riv/nazevZdroje	Folia Biologica
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...vavai/riv/projekt	Immunotherapy of MHC class I - Tumours: Modulation of the MHC Class I Expression by Demethylation, Selection of Proper Adjuvants Tumours of human papillomavirus origin with different expression of MHC class I molecules: theoretical principles of immunotherapy. Combined Immunotherapy of Tumours Induced by Human Papillomavirus Induction of immunity against HPV16 E6/E7 oncogenes-induced tumours with peptide- and dendritic cell-based vaccines; immunotherapy of minimal residual tumour disease.
http://linked.open...UplatneniVysledku	2006
http://linked.open...v/svazekPeriodika	52
http://linked.open...iv/tvurceVysledku	Bubeník, Jan
http://linked.open...n/vavai/riv/zamer	Molekulárně genetické a buněčné základy klíčových biologických procesů: genová exprese, onkogeneze, replikace virů, imunita a vývoj organismů
issn	0015-5500
number of pages	2 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Human papillomavirus (HPV) and HPV-associated tumour vaccines Human papillomavirus (HPV) and HPV-associated tumour vaccines

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