About: Intranuclear anchoring of repetitive DNA sequences: centromeres, telomeres, and ribosomal DNA

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Intranuclear anchoring of repetitive DNA sequences: centromeres, telomeres, and ribosomal DNA Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Centromeres, telomeres, and ribosomal gene clusters consist of repetitive DNA sequences. To assess their contributions to the spatial organization of the interphase genome, their interactions with the nucleoskeleton were examined in quiescent and activated human lymphocytes. The results demonstrate that: (a) the various repetitive DNA sequences differ significantly in their intranuclear anchoring, (b) telomeric rather than centromeric DNA sequences form stable attachments to the nucleoskeleton, and (c) different attachment mechanisms might be responsible for the interaction of ribosomal genes with the nucleoskeleton. Centromeres, telomeres, and ribosomal gene clusters consist of repetitive DNA sequences. To assess their contributions to the spatial organization of the interphase genome, their interactions with the nucleoskeleton were examined in quiescent and activated human lymphocytes. The results demonstrate that: (a) the various repetitive DNA sequences differ significantly in their intranuclear anchoring, (b) telomeric rather than centromeric DNA sequences form stable attachments to the nucleoskeleton, and (c) different attachment mechanisms might be responsible for the interaction of ribosomal genes with the nucleoskeleton. (en) Centromery, telomery a seskupení ribozomálních genů sestávají z repetitivních sekvencí DNA. Za účelem zjištění podílu těchto sekvencí na prostorovém uspořádání genomu v interfázi byly sledovány jejich interakce s nukleoskeletem v aktivovaných a klidových lidských lymfocytech. Výsledky ukazují, že: 1) různé repetitivní sekvence se značně liší způsobem zakotvení v buněčném jádře, 2) telomerní spíše než centromerní DNA sekvence jsou zakotveny na nukleoskeletu, 3) interakce ribozomálních genů s nukleoskeletom mohou být způsobeny různými factory. (cs)
Title	Intranuclear anchoring of repetitive DNA sequences: centromeres, telomeres, and ribosomal DNA Intranuclear anchoring of repetitive DNA sequences: centromeres, telomeres, and ribosomal DNA (en) Vnitrojaderné zakotvení repetitivních sekvencí DNA: centromery, telomery a ribozomální DNA (cs)
skos:prefLabel	Intranuclear anchoring of repetitive DNA sequences: centromeres, telomeres, and ribosomal DNA Intranuclear anchoring of repetitive DNA sequences: centromeres, telomeres, and ribosomal DNA (en) Vnitrojaderné zakotvení repetitivních sekvencí DNA: centromery, telomery a ribozomální DNA (cs)
skos:notation	RIV/68378041:_____/99:00173354!RIV08-AV0-68378041
http://linked.open.../vavai/riv/strany	1409;1418
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(KSK2052601), P(ME 279), Z(AV0Z5039906)
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Hozák, Pavel Philimonenko, Vlada
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	743107
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/99:00173354
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	DNA (en)
http://linked.open.../riv/klicoveSlovo	DNA
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[5800011E28B5]
http://linked.open...i/riv/nazevZdroje	Journal of Cell Biology
http://linked.open...in/vavai/riv/obor	EA
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	http://linked.opendata.cz/resource/domain/vavai/projekt/ME%20279 Genome structure and expression
http://linked.open...UplatneniVysledku	1999
http://linked.open...v/svazekPeriodika	147
http://linked.open...iv/tvurceVysledku	Almeder, M. Hozák, Pavel Philimonenko, Vlada Wachtler, F. Schöfer, CH. Weipoltshammer, K. Frei, K.
http://linked.open...n/vavai/riv/zamer	The molecular and cellular basis of selected human diseases, mechanisms of normal and pathological function, principles of diagnosis and therapy
issn	0021-9525
number of pages	10 (xsd:int)

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software