About: Cholesterol-modified superporous poly(2-hydroxyethyl methacrylate) scaffolds for tissue engineering

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Cholesterol-modified superporous poly(2-hydroxyethyl methacrylate) scaffolds for tissue engineering Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Modifications of poly(2-hydroxyethyl methacrylate) (PHEMA) with cholesterol and laminin have been developed to design scaffolds that promote cell–surface interaction. Cholesterol- (P(HEMA–CHLMA)) and laminin-modified (LN–PHEMA) superporous PHEMA scaffolds have been prepared by the bulk radical copolymerization of 2-hydroxyethyl methacrylate (HEMA), cholesterol methacrylate (CHLMA) and the cross-linking agent ethylene imethacrylate in the presence of ammonium oxalate crystals to introduce interconnected superpores in the matrix. Neat PHEMA and laminin-modified PHEMA scaffolds facilitated MSC attachment, but did not support cell spreading and proliferation; the viability of the attached cells decreased with time of cultivation. In contrast, MSCs spread and proliferated on P(HEMA–CHLMA) and LN-P(HEMA–CHLMA) hydrogels. Modifications of poly(2-hydroxyethyl methacrylate) (PHEMA) with cholesterol and laminin have been developed to design scaffolds that promote cell–surface interaction. Cholesterol- (P(HEMA–CHLMA)) and laminin-modified (LN–PHEMA) superporous PHEMA scaffolds have been prepared by the bulk radical copolymerization of 2-hydroxyethyl methacrylate (HEMA), cholesterol methacrylate (CHLMA) and the cross-linking agent ethylene imethacrylate in the presence of ammonium oxalate crystals to introduce interconnected superpores in the matrix. Neat PHEMA and laminin-modified PHEMA scaffolds facilitated MSC attachment, but did not support cell spreading and proliferation; the viability of the attached cells decreased with time of cultivation. In contrast, MSCs spread and proliferated on P(HEMA–CHLMA) and LN-P(HEMA–CHLMA) hydrogels. (en)
Title	Cholesterol-modified superporous poly(2-hydroxyethyl methacrylate) scaffolds for tissue engineering Cholesterol-modified superporous poly(2-hydroxyethyl methacrylate) scaffolds for tissue engineering (en)
skos:prefLabel	Cholesterol-modified superporous poly(2-hydroxyethyl methacrylate) scaffolds for tissue engineering Cholesterol-modified superporous poly(2-hydroxyethyl methacrylate) scaffolds for tissue engineering (en)
skos:notation	RIV/68378041:_____/09:00330578!RIV10-AV0-68378041
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(KAN200520804), Z(AV0Z40500505), Z(AV0Z50390512)
http://linked.open...iv/cisloPeriodika	27
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Syková, Eva Kubinová, Šárka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	306992
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/09:00330578
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cell adhesion; cell viability; hydrogel (en)
http://linked.open.../riv/klicoveSlovo	cell adhesion hydrogel cell viability
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[11B88C47B401]
http://linked.open...i/riv/nazevZdroje	Biomaterials
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Biocompatible nanofiber scaffolds forming novel drug matrices for the application of biologically and pharmacologically active substances
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	30
http://linked.open...iv/tvurceVysledku	Horák, Daniel Syková, Eva Kubinová, Šárka
http://linked.open...ain/vavai/riv/wos	000269330400019
http://linked.open...n/vavai/riv/zamer	Progresivní makromolekulární materiály a supramolekulární systémy: syntéza a studium vlastností, jevů a možností využití pro speciální aplikace a moderní technologie Molekulární, buněčné a systémové mechanizmy závažných onemocnění lidského organizmu, jejich diagnostika, terapie a farmakoterapie
issn	0142-9612
number of pages	9 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Cholesterol-modified superporous poly(2-hydroxyethyl methacrylate) scaffolds for tissue engineering Cholesterol-modified superporous poly(2-hydroxyethyl methacrylate) scaffolds for tissue engineering Cholesterol-modified superporous poly(2-hydroxyethyl methacrylate) scaffolds for tissue engineering Cholesterol-modified superporous poly(2-hydroxyethyl methacrylate) scaffolds for tissue engineering

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software