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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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Description
  • Tato studie souhrnně pojednává o biotransformaci styrénu, včetně minoritních metabolických cest, a dává do vztahu metabolismus styrénu k jeho genotoxickým účinkům a možným účinkům karcinogenním. V práci jsou diskutovány faktory individuální vnímavosti v souvislosti s polymorfismy biotransformačních genů a s individuální DNA reparační kapacitou, jakož i nonlinearita ve vztazích dávka-účinek a jejich důsledky pro hodnocení rizika expozice styrénu. (cs)
  • This report reviews styrene biotransformation, including minor metabolic routes, and relates metabolism to the genotoxic effects and possible styrene-related carcinogenicity. Individual susceptibility depending on metabolism polymorphisms and individual DNA repair capacity as well as the dependence of the nonlinearity of the dose-response relationships in the species in question and the consequences for risk evaluation are analysed.
  • This report reviews styrene biotransformation, including minor metabolic routes, and relates metabolism to the genotoxic effects and possible styrene-related carcinogenicity. Individual susceptibility depending on metabolism polymorphisms and individual DNA repair capacity as well as the dependence of the nonlinearity of the dose-response relationships in the species in question and the consequences for risk evaluation are analysed. (en)
Title
  • Styrene metabolism, genotoxicity, an potential carcinogenicity
  • Styrene metabolism, genotoxicity, an potential carcinogenicity (en)
  • Metabolismus styrénu, jeho genotoxické a potenciálně karcinogenní účinky (cs)
skos:prefLabel
  • Styrene metabolism, genotoxicity, an potential carcinogenicity
  • Styrene metabolism, genotoxicity, an potential carcinogenicity (en)
  • Metabolismus styrénu, jeho genotoxické a potenciálně karcinogenní účinky (cs)
skos:notation
  • RIV/68378041:_____/06:00043878!RIV07-AV0-68378041
http://linked.open.../vavai/riv/strany
  • 805;853
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA310/03/0437), Z(AV0Z50390512)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 502356
http://linked.open...ai/riv/idVysledku
  • RIV/68378041:_____/06:00043878
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Styrene; Biotransformation; DNA and chromosomal damage (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • FR - Francouzská republika
http://linked.open...ontrolniKodProRIV
  • [25E78A5FD9A6]
http://linked.open...i/riv/nazevZdroje
  • Drug Metabolism Reviews
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 38
http://linked.open...iv/tvurceVysledku
  • Hemminki, K.
  • Naccarati, Alessio
  • Vodička, Pavel
  • Vodičková, Ludmila
  • Oesch, F.
  • Oesch-Bartlomowicz, B.
  • Koskinen, M.
http://linked.open...n/vavai/riv/zamer
issn
  • 0360-2532
number of pages
is http://linked.open...avai/riv/vysledek of
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