About: The genotoxic effect of carcinogenic PAHs, their artificial and environmental mixtures (EOM), on human diploid lung fibroblasts

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About: The genotoxic effect of carcinogenic PAHs, their artificial and environmental mixtures (EOM), on human diploid lung fibroblasts Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Studie genotoxického účinku karcinogenních c-PAU a jejich binárních a modelových směsí a také environmentálních směsí EOM (extrahovatelné organické látky adsorbované na respirabilních částicích vzduchu) za použití normálních lidských diploidních plicních buněk (HEL). DNA adukty byly stanoveny pomocí 32P-labelingu a expresí proteinů p53 a p21WAFl metodou western blottingu. DB[aI] i B[a]P byly vybrány jako vhodné pro hodnocení genotoxického účinku jiných c-PAU přítomných v binárních směsích (cs) The study of the genotoxic effect of single c-PAHs and their binary and artificial mixtures, as well as the environmental mixtures such as EOM (extractable organic matter adsorbed to respirable air particles) using normal human diploid lung fibroblasts (HEL). DNA adducts were determined by 32P-postlabelling and the expression of p53 and p21WAF1 proteins by western blotting. Both DB[al]P and B[a]P were chosen to assess the genotoxic effect of other c-PAHs when present in binary mixtures The study of the genotoxic effect of single c-PAHs and their binary and artificial mixtures, as well as the environmental mixtures such as EOM (extractable organic matter adsorbed to respirable air particles) using normal human diploid lung fibroblasts (HEL). DNA adducts were determined by 32P-postlabelling and the expression of p53 and p21WAF1 proteins by western blotting. Both DB[al]P and B[a]P were chosen to assess the genotoxic effect of other c-PAHs when present in binary mixtures (en)
Title	The genotoxic effect of carcinogenic PAHs, their artificial and environmental mixtures (EOM), on human diploid lung fibroblasts The genotoxic effect of carcinogenic PAHs, their artificial and environmental mixtures (EOM), on human diploid lung fibroblasts (en) Genotoxický účinek karcinogenních c-PAU a jejich binárních a modelových směsí, a také environmentálních směsí (EOM) na lidské diploidní plicní fibroblasty (cs)
skos:prefLabel	The genotoxic effect of carcinogenic PAHs, their artificial and environmental mixtures (EOM), on human diploid lung fibroblasts The genotoxic effect of carcinogenic PAHs, their artificial and environmental mixtures (EOM), on human diploid lung fibroblasts (en) Genotoxický účinek karcinogenních c-PAU a jejich binárních a modelových směsí, a také environmentálních směsí (EOM) na lidské diploidní plicní fibroblasty (cs)
skos:notation	RIV/68378041:_____/04:00100991!RIV/2005/AV0/A19005/N
http://linked.open.../vavai/riv/strany	109;121
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(SL/740/5/03), Z(AV0Z5039906)
http://linked.open...iv/cisloPeriodika	-
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Šrám, Radim Binková, Blanka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	565406
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/04:00100991
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	PAHs;Human lung fibroblasts (en)
http://linked.open.../riv/klicoveSlovo	Human lung fibroblasts PAHs
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[0AA2C752884D]
http://linked.open...i/riv/nazevZdroje	Mutation Research
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Air pollution and health protection
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	547
http://linked.open...iv/tvurceVysledku	Binková, Blanka Šrám, Radim
http://linked.open...n/vavai/riv/zamer	The molecular and cellular basis of selected human diseases, mechanisms of normal and pathological function, principles of diagnosis and therapy
issn	0027-5107
number of pages	13 (xsd:int)

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