About: Cytogenetic analysis using fluorescence in situ hybridization (FISH) to evaluate occupational exposure to carcinogens

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About: Cytogenetic analysis using fluorescence in situ hybridization (FISH) to evaluate occupational exposure to carcinogens Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Groups occupationally exposed to 1,3-butadiene (BD), acrylonitrile, ethyl benzene and benzene in petrochemical industry, and carcinogenic polycyclic aromatic hydrocarbons (c-PAHs) from ambient air were followed both by conventional cytogenetic analysis and FISH painting for chromosomes # 1 and # 4, in total 383 subjects, including controls. The findings indicate that the method FISH with whole chromosome painting seems to be more sensitive to detect chromosomal injury by occupational exposure to carcinogens than the conventional method Groups occupationally exposed to 1,3-butadiene (BD), acrylonitrile, ethyl benzene and benzene in petrochemical industry, and carcinogenic polycyclic aromatic hydrocarbons (c-PAHs) from ambient air were followed both by conventional cytogenetic analysis and FISH painting for chromosomes # 1 and # 4, in total 383 subjects, including controls. The findings indicate that the method FISH with whole chromosome painting seems to be more sensitive to detect chromosomal injury by occupational exposure to carcinogens than the conventional method (en) Byly sledovány skupiny osob profesionálně exponované 1,3-butadienu (BD), akrylonitrilu, etylbenzenu a benzenu v petrochemickém průmyslu, a osoby exponované karcinogenním polycyklickým aromatickým uhlovodíkům (c-PAU) z ovzduší. Celkem bylo sledováno 383 osob, včetně kontrol, metodou konvenční cytogenetické analýzy a metodou FISH (barvení chromosomů 1 a 4). Výsledky ukazují, že metoda FISH se zdá být citlivější pro detekci poškození chromosomů při profesionální expozici než konvenční metoda (cs)
Title	Cytogenetic analysis using fluorescence in situ hybridization (FISH) to evaluate occupational exposure to carcinogens Cytogenetická analýza pomocí fluorescence in situ hybridization (FISH) při hodnocení profesionální expozice karcinogenům (cs) Cytogenetic analysis using fluorescence in situ hybridization (FISH) to evaluate occupational exposure to carcinogens (en)
skos:prefLabel	Cytogenetic analysis using fluorescence in situ hybridization (FISH) to evaluate occupational exposure to carcinogens Cytogenetická analýza pomocí fluorescence in situ hybridization (FISH) při hodnocení profesionální expozice karcinogenům (cs) Cytogenetic analysis using fluorescence in situ hybridization (FISH) to evaluate occupational exposure to carcinogens (en)
skos:notation	RIV/68378041:_____/04:00100990!RIV/2005/AV0/A19005/N
http://linked.open.../vavai/riv/strany	335;344
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(SI/340/2/00), Z(AV0Z5039906)
http://linked.open...iv/cisloPeriodika	-
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Šrám, Radim Binková, Blanka Beskid, Olena Šmerhovský, Zdeněk
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	559195
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/04:00100990
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Chromosomal aberrations;Fluorescence in situ hybridization (en)
http://linked.open.../riv/klicoveSlovo	Chromosomal aberrations Fluorescence in situ hybridization
http://linked.open...odStatuVydavatele	IE - Irsko
http://linked.open...ontrolniKodProRIV	[68877436C100]
http://linked.open...i/riv/nazevZdroje	Toxicology Letters
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Impact of complex mixtures in polluted air on the health of risk population groups( Program Air pollution and health)
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	149
http://linked.open...iv/tvurceVysledku	Beskid, Olena Binková, Blanka Rössner, P. Šmerhovský, Zdeněk Šrám, Radim
http://linked.open...n/vavai/riv/zamer	The molecular and cellular basis of selected human diseases, mechanisms of normal and pathological function, principles of diagnosis and therapy
issn	0378-4274
number of pages	10 (xsd:int)

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