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  • We empirically tested the long-standing hypothesis of codivergence of New World arenaviruses (NWA) with their hosts. With the exception of viruses from North America, no phylogenetically codivergent pattern between NWA and their hosts was found. We found that different virus clades were clustered differently and that Clade B with members pathogenic to humans was randomly distributed across the rodent phylogeny. Furthermore, viral relatedness within Clade B was significantly explained by the geographic overlap of their hosts’ ranges rather than host relatedness, indicating that they are capable of host switching opportunistically. This has important bearings on their potential to become panzootic. Together, these analyses suggest that NWA have not codiverged with their hosts and instead have evolved predominantly via host switching.
  • We empirically tested the long-standing hypothesis of codivergence of New World arenaviruses (NWA) with their hosts. With the exception of viruses from North America, no phylogenetically codivergent pattern between NWA and their hosts was found. We found that different virus clades were clustered differently and that Clade B with members pathogenic to humans was randomly distributed across the rodent phylogeny. Furthermore, viral relatedness within Clade B was significantly explained by the geographic overlap of their hosts’ ranges rather than host relatedness, indicating that they are capable of host switching opportunistically. This has important bearings on their potential to become panzootic. Together, these analyses suggest that NWA have not codiverged with their hosts and instead have evolved predominantly via host switching. (en)
Title
  • Complex patterns of host switching in New World arenaviruses
  • Complex patterns of host switching in New World arenaviruses (en)
skos:prefLabel
  • Complex patterns of host switching in New World arenaviruses
  • Complex patterns of host switching in New World arenaviruses (en)
skos:notation
  • RIV/68081766:_____/12:00377735!RIV13-AV0-68081766
http://linked.open...avai/predkladatel
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  • I, Z(AV0Z60930519)
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  • 16
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  • 128188
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  • RIV/68081766:_____/12:00377735
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  • AxParafit; codivergence; cophylogeny; Phylocom; reconciliation; viral haemorrhagic fever (en)
http://linked.open.../riv/klicoveSlovo
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  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [6D553F7F1821]
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  • Molecular Ecology
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  • 21
http://linked.open...iv/tvurceVysledku
  • Martínková, Natália
  • Bayerlová, M.
  • Irwin, N. R.
  • Missa, O.
http://linked.open...ain/vavai/riv/wos
  • 000306897500020
http://linked.open...n/vavai/riv/zamer
issn
  • 0962-1083
number of pages
http://bibframe.org/vocab/doi
  • 10.1111/j.1365-294X.2012.05663.x
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