About: Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug

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About: Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	It has been determined how the Y-family translesion DNA polymerase eta processes a DNA double-base lesion derived from 1,2-GG intrastrand cross-links of a new antitumor PtII complex containing a bulky carrier ligand, namely [PtCl2(cis-1,4-dach)] (dach=diaminocyclohexane). It has been determined how the Y-family translesion DNA polymerase eta processes a DNA double-base lesion derived from 1,2-GG intrastrand cross-links of a new antitumor PtII complex containing a bulky carrier ligand, namely [PtCl2(cis-1,4-dach)] (dach=diaminocyclohexane). (en)
Title	Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug (en)
skos:prefLabel	Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug (en)
skos:notation	RIV/68081707:_____/12:00386041!RIV13-AV0-68081707
http://linked.open...avai/predkladatel	Biofyzikální ústav AV ČR, v.v.i.
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GAP205/11/0856), P(GAP301/10/0598), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika	48
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Brabec, Viktor Kašpárková, Jana Malina, Jaroslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	174294
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/12:00386041
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	DNA polymerase; platinum; calorimetry (en)
http://linked.open.../riv/klicoveSlovo	DNA polymerase calorimetry platinum
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[32F804CAAF4F]
http://linked.open...i/riv/nazevZdroje	Chemistry - A European Journal
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Thermodynamics of DNA damaged by physical and chemical agents Metallodrugs based on osmium, platinum and ruthenium complexes. From mechanistic studies to novel, more efficient chemotherapy of cancer
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	18
http://linked.open...iv/tvurceVysledku	Brabec, Viktor Kašpárková, Jana Malina, Jaroslav Margiotta, N. Natile, G.
http://linked.open...ain/vavai/riv/wos	000311306700029
http://linked.open...n/vavai/riv/zamer	Genome and epigenome: 1D and 3D Structure, Dynamics, Interactions with Proteins and Functions
issn	0947-6539
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.1002/chem.201202117
is http://linked.open...avai/riv/vysledek of	Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug

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