About: Role of HMGB Proteins in Chromatin Dynamics and Telomere Maintenance in Arabidopsis thaliana

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About: Role of HMGB Proteins in Chromatin Dynamics and Telomere Maintenance in Arabidopsis thaliana Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Chromosome stability is conditioned by functional chromatin structure of chromosome ends - telomeres. Organisation and regulation of telomere maintenance represent a complex process whose details still remain enigmatic, especially in plants. Several telomere-binding or telomere-associated proteins and distinct epigenetic marks have been shown to influence telomere length and telomerase activity. HMGB proteins play important role in dynamic changes of chromatin structure and are involved in regulation of cellular processes of key importance, such as replication, transcription, recombination and DNA-repair. HMGB proteins in plants are more diversified than in other eukaryotes. Here, we summarise the roles of plant HMGB proteins in regulation of chromatin structure and dynamics and report on the newly identified role of AtHMGB1 protein in the regulation of plant telomere length. Astonishingly, contrary to mice mHMGB1 homologue, AtHMGB1 does not affect telomerase activity and AtHMGB1 loss or overexpression does not cause any obvious changes in chromatin architecture. Chromosome stability is conditioned by functional chromatin structure of chromosome ends - telomeres. Organisation and regulation of telomere maintenance represent a complex process whose details still remain enigmatic, especially in plants. Several telomere-binding or telomere-associated proteins and distinct epigenetic marks have been shown to influence telomere length and telomerase activity. HMGB proteins play important role in dynamic changes of chromatin structure and are involved in regulation of cellular processes of key importance, such as replication, transcription, recombination and DNA-repair. HMGB proteins in plants are more diversified than in other eukaryotes. Here, we summarise the roles of plant HMGB proteins in regulation of chromatin structure and dynamics and report on the newly identified role of AtHMGB1 protein in the regulation of plant telomere length. Astonishingly, contrary to mice mHMGB1 homologue, AtHMGB1 does not affect telomerase activity and AtHMGB1 loss or overexpression does not cause any obvious changes in chromatin architecture. (en)
Title	Role of HMGB Proteins in Chromatin Dynamics and Telomere Maintenance in Arabidopsis thaliana Role of HMGB Proteins in Chromatin Dynamics and Telomere Maintenance in Arabidopsis thaliana (en)
skos:prefLabel	Role of HMGB Proteins in Chromatin Dynamics and Telomere Maintenance in Arabidopsis thaliana Role of HMGB Proteins in Chromatin Dynamics and Telomere Maintenance in Arabidopsis thaliana (en)
skos:notation	RIV/68081707:_____/11:00440863!RIV15-AV0-68081707
http://linked.open...avai/riv/aktivita	I P Z
http://linked.open...avai/riv/aktivity	I, P(GA204/08/1530), P(GP521/08/P452), Z(MSM0021622415)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Fojtová, Miloslava Fajkus, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	227452
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/11:00440863
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	HMGB; telomere shortening/elongation; plants (en)
http://linked.open.../riv/klicoveSlovo	plants HMGB telomere shortening/elongation
http://linked.open...odStatuVydavatele	AE - Stát Spojené arabské emiráty
http://linked.open...ontrolniKodProRIV	[EB31A87A31F8]
http://linked.open...i/riv/nazevZdroje	Current Protein and Peptide Science
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Characterisation of functional diversity of the plant-specific SMH family of proteins Understanding of HMGB1 protein involvement in maintaining genome stability
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	12
http://linked.open...iv/tvurceVysledku	Fajkus, Jiří Fojtová, Miloslava Mokroš, P. Grasser, K. D. Schrumpfová, P.
http://linked.open...ain/vavai/riv/wos	000291109700005
http://linked.open...n/vavai/riv/zamer	Molecular basis of cell and tissue regulations
issn	1389-2037
number of pages	7 (xsd:int)

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