About: Electrode potential-controlled DNA damage in the presence of copper ions and their complexes.

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About: Electrode potential-controlled DNA damage in the presence of copper ions and their complexes. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Supercoiled (sc) DNA immobilized at the surface of a hanging mercury drop electrode was cleaved by reactive oxygen species generated by an electrochemically modulated reaction of copper ions, hydrogen peroxide and/or oxygen. The cleavage was observed in a certain potential region where redox cycling of DNA-bound Cu(II)/Cu(I) took place. In the presence of 1, 10-phenanthroline the maximum efficiency of DNA cleavage was shifted to more negative potentials and the effect was enhanced. Supercoiled (sc) DNA immobilized at the surface of a hanging mercury drop electrode was cleaved by reactive oxygen species generated by an electrochemically modulated reaction of copper ions, hydrogen peroxide and/or oxygen. The cleavage was observed in a certain potential region where redox cycling of DNA-bound Cu(II)/Cu(I) took place. In the presence of 1, 10-phenanthroline the maximum efficiency of DNA cleavage was shifted to more negative potentials and the effect was enhanced. (en)
Title	Electrode potential-controlled DNA damage in the presence of copper ions and their complexes. Electrode potential-controlled DNA damage in the presence of copper ions and their complexes. (en)
skos:prefLabel	Electrode potential-controlled DNA damage in the presence of copper ions and their complexes. Electrode potential-controlled DNA damage in the presence of copper ions and their complexes. (en)
skos:notation	RIV/68081707:_____/02:17023003!RIV/2003/GA0/A17003/N
http://linked.open.../vavai/riv/strany	25;27
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA204/00/D049), P(GV204/97/K084), P(IAA4004108), Z(AV0Z5004920)
http://linked.open...iv/cisloPeriodika	1/2
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Paleček, Emil Kubičárová, Tatiana Havran, Luděk Fojta, Miroslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	644747
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/02:17023003
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	DNA demage; mercury electrode; copper ions (en)
http://linked.open.../riv/klicoveSlovo	copper ions mercury electrode DNA demage
http://linked.open...odStatuVydavatele	CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV	[E5826A64676D]
http://linked.open...i/riv/nazevZdroje	Bioelectrochemistry
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Influence of chemical modification of DNA and synthetic oligonucleotides on their electrochemical behaviour Electrodes modified with nucleic acids and proteins.New tools in biochemical and biomedical research. Development of electrochemical biodetectors for DNA damage
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	55
http://linked.open...iv/tvurceVysledku	Havran, Luděk Paleček, Emil Kubičárová, Tatiana Fojta, Miloslav
http://linked.open...n/vavai/riv/zamer	Biophysical properties of living systems and their changes under the influence of environmental factors
issn	1567-5394
number of pages	3 (xsd:int)

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