About: Dibenzo[a,c]cyclooctadiene Lignans of the Genus Schisandra: Importance, Isolation, and Determination

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About: Dibenzo[a,c]cyclooctadiene Lignans of the Genus Schisandra: Importance, Isolation, and Determination Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The drug Wuweizi (dried fruits of Schisandra chinensis or S. sphenanthera) is one of important medicinal means used in the Oriental medicine. The lignans of dibenzo[a,c]cyklooctadiene type are major constituents. The content of major lignans (schizandrin, deoxyschizandrin, gomisin A, gomisin N, -schizandrin, wuweizisu C) in commercially available drugs ranges usually between 3-5% The present paper biefly comments the isolation and biological activity of the lignans, and is especially concerned with analytical methods (TLC and HPLC) for the determination of the drug fingerprint and methods for the determination of constituents in drugs, mixtures and biological materials. HPLC methods using RP silica bonded phases and diluted methanol, acetonitrile (or a mixture of both) are most important for these purposes. Electromigration methods are less suitable, and the importance of hyphenation procedures is practically negligible. The drug Wuweizi (dried fruits of Schisandra chinensis or S. sphenanthera) is one of important medicinal means used in the Oriental medicine. The lignans of dibenzo[a,c]cyklooctadiene type are major constituents. The content of major lignans (schizandrin, deoxyschizandrin, gomisin A, gomisin N, -schizandrin, wuweizisu C) in commercially available drugs ranges usually between 3-5% The present paper biefly comments the isolation and biological activity of the lignans, and is especially concerned with analytical methods (TLC and HPLC) for the determination of the drug fingerprint and methods for the determination of constituents in drugs, mixtures and biological materials. HPLC methods using RP silica bonded phases and diluted methanol, acetonitrile (or a mixture of both) are most important for these purposes. Electromigration methods are less suitable, and the importance of hyphenation procedures is practically negligible. (en)
Title	Dibenzo[a,c]cyclooctadiene Lignans of the Genus Schisandra: Importance, Isolation, and Determination Dibenzo[a,c]cyclooctadiene Lignans of the Genus Schisandra: Importance, Isolation, and Determination (en)
skos:prefLabel	Dibenzo[a,c]cyclooctadiene Lignans of the Genus Schisandra: Importance, Isolation, and Determination Dibenzo[a,c]cyclooctadiene Lignans of the Genus Schisandra: Importance, Isolation, and Determination (en)
skos:notation	RIV/67985858:_____/04:00338609!RIV10-AV0-67985858
http://linked.open...avai/riv/aktivita	P V Z
http://linked.open...avai/riv/aktivity	P(GA203/01/0550), V, Z(AV0Z4072921)
http://linked.open...iv/cisloPeriodika	1-2
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Bártlová, Milena Sovová, Helena
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav chemických procesů AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	560411
http://linked.open...ai/riv/idVysledku	RIV/67985858:_____/04:00338609
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	lignans; isolation; determination (en)
http://linked.open.../riv/klicoveSlovo	isolation determination lignans
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[589870BCC06A]
http://linked.open...i/riv/nazevZdroje	Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences
http://linked.open...in/vavai/riv/obor	CI
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Supercritical fluid extraction of plant metabolites usable in the treatment and prevention of the diseases of heart and vessels
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	812
http://linked.open...iv/tvurceVysledku	Opletal, L. Sovová, Helena Bártlová, Milena
http://linked.open...ain/vavai/riv/wos	000225410300025
http://linked.open...n/vavai/riv/zamer	Theoretical fundamentals of chemical processes: equilibrium and dynamic behavior of multiphase reacting systems
issn	1570-0232
number of pages	15 (xsd:int)

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