About: Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids

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About: Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	White adipose tissue plays an active role in the amelioration of obesity and the improvement of glucose homeostasis by combining LC n-3 PUFA intake and calorie restriction in mice fed high-fat diet. Specifically in the epididymal fat in the abdomen, but not in other fat depots, synergistic induction of mitochondrial oxidative capacity and lipid catabolism was observed, resulting in increased oxidation of metabolic fuels in the absence of mitochondrial uncoupling, while low-grade inflammation was suppressed, reflecting changes in tissue levels of anti-inflammatory lipid mediators, namely 15-Deoxy-12,15-prostaglandin J2 and protectin D1 White adipose tissue plays an active role in the amelioration of obesity and the improvement of glucose homeostasis by combining LC n-3 PUFA intake and calorie restriction in mice fed high-fat diet. Specifically in the epididymal fat in the abdomen, but not in other fat depots, synergistic induction of mitochondrial oxidative capacity and lipid catabolism was observed, resulting in increased oxidation of metabolic fuels in the absence of mitochondrial uncoupling, while low-grade inflammation was suppressed, reflecting changes in tissue levels of anti-inflammatory lipid mediators, namely 15-Deoxy-12,15-prostaglandin J2 and protectin D1 (en)
Title	Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids (en)
skos:prefLabel	Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids (en)
skos:notation	RIV/67985823:_____/11:00364489!RIV12-AV0-67985823
http://linked.open...avai/predkladatel	Fyziologický ústav AV ČR, v.v.i.
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0520), P(GA303/08/0664), Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika	10
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Kopecký, Jan Flachs, Pavel Hensler, Michal Macek Jílková, Zuzana Kůs, Vladimír Rossmeisl, Martin Kuda, Ondřej Janovská, Petra Tsenov, Grygoriy Zouhar, Petr Svobodová, Michaela
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	233799
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/11:00364489
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	15-Deoxy-Delta(12,15)-prostaglandin J(2); DHA; EPA; fish oil; white adipose tissue; metabolic syndrome (en)
http://linked.open.../riv/klicoveSlovo	DHA EPA fish oil 15)-prostaglandin J(2) 15-Deoxy-Delta(12 white adipose tissue metabolic syndrome
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[E57EBFA177D3]
http://linked.open...i/riv/nazevZdroje	Diabetologia
http://linked.open...in/vavai/riv/obor	FB
http://linked.open...ichTvurcuVysledku	11 (xsd:int)
http://linked.open...cetTvurcuVysledku	14 (xsd:int)
http://linked.open...vavai/riv/projekt	Center for Applied Genomics Induction of mitochondria in white fat: a common target for treatments ameliorating obesity and insulin resistance
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	54
http://linked.open...iv/tvurceVysledku	Kopecký, Jan Flachs, Pavel Hensler, Michal Macek Jílková, Zuzana Kůs, Vladimír Janovská, Petra Kuda, Ondřej Mohamed-Ali, V. Papp, E. Rossmeisl, Martin Rühl, R. Svobodová, Michaela Tsenov, Grygoriy Zouhar, Petr
http://linked.open...ain/vavai/riv/wos	000294683000019
http://linked.open...n/vavai/riv/zamer	Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka
issn	0012-186X
number of pages	13 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s00125-011-2233-2
is http://linked.open...avai/riv/vysledek of	Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids

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