About: Use of rat genomics for investigating the metabolic syndrome

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The spontaneously hypertensive rat (SHR) is the most widely used animal model of essential hypertension and accompanying metabolic isturbances. In this model, the use of whole genome sequencing and gene expression profiling techniques, linkage and correlation analyses in recombinant inbred straíns, and in vitro and in vivo functional studies in congenic and transgenic lines has recently enabled molecular identification of quantitative trait loci relevant to the metabolic syndrome at the molecular level The spontaneously hypertensive rat (SHR) is the most widely used animal model of essential hypertension and accompanying metabolic isturbances. In this model, the use of whole genome sequencing and gene expression profiling techniques, linkage and correlation analyses in recombinant inbred straíns, and in vitro and in vivo functional studies in congenic and transgenic lines has recently enabled molecular identification of quantitative trait loci relevant to the metabolic syndrome at the molecular level (en)
Title	Use of rat genomics for investigating the metabolic syndrome Use of rat genomics for investigating the metabolic syndrome (en)
skos:prefLabel	Use of rat genomics for investigating the metabolic syndrome Use of rat genomics for investigating the metabolic syndrome (en)
skos:notation	RIV/67985823:_____/10:00341835!RIV11-GA0-67985823
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0520), P(1P05ME791), P(GA301/06/0028), P(GA301/08/0166), P(IAA500110604), Z(AV0Z50110509)
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Pravenec, Michal
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	294710
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/10:00341835
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	spontaneously hypertensive rat; metabolic syndrome; genetics (en)
http://linked.open.../riv/klicoveSlovo	spontaneously hypertensive rat genetics metabolic syndrome
http://linked.open...ontrolniKodProRIV	[91F449989D87]
http://linked.open...i/riv/mistoVydani	New York
http://linked.open...i/riv/nazevZdroje	Rat Genomics
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...v/pocetStranKnihy	461 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...vavai/riv/projekt	Positional cloning of a gene on chromosome 10 that is responsible for hypertension and metabolic defects in the spontaneously hypertensive rat Genetic analysis of the role of mitochondria in the pathogenesis of metabolic syndrome studied in new rat conplastic strains Center for Applied Genomics Genetic determinants of cardiac mass and response to infarction in recombinant inbred rats Pathogenesis of spontaneous hypertension: integrated analysis of intermediary phenotypes of autonomic/sympathetic system and gene expression profiles in rat recombinant inbred strains
http://linked.open...UplatneniVysledku	2010
http://linked.open...iv/tvurceVysledku	Pravenec, Michal
http://linked.open...n/vavai/riv/zamer	Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka
number of pages	12 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Humana Press
https://schema.org/isbn	978-1-60327-388-6
is http://linked.open...avai/riv/vysledek of	Use of rat genomics for investigating the metabolic syndrome

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