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  • Studovali jsme vztah polymorfismu Igf2 genu ke krevnímu tlaku a plasmatickým lipidům u pražských hereditárně hypertenzních potkanů, kteří představují model metabolického syndromu. Sekvenční analýza cDNA odhalila inserci 14 nukleotidů v tomto genu HTG potkanů. Polymorfismus Igf2 genu se zdá být odpovědný za část poruch lipidového metabolismu, ale jeho vztah k regulaci krevního tlaku zatím nebyl objasněn (cs)
  • We have studied the relationship of Igf2 gene polymorphism to blood pressure and plasma lipids in Prague hereditary hypertriglyceridemic rats (HTG) which represent a model of metabolic syndrome. Sequence analysis of cDNA revealed insertion of 14 nucleotides in HTG gene. Polymorphism in Igf2 gene may be responsible for abnormal lipid metabolism in HTG, but its role in blood pressure regulation remains to be elucidated
  • We have studied the relationship of Igf2 gene polymorphism to blood pressure and plasma lipids in Prague hereditary hypertriglyceridemic rats (HTG) which represent a model of metabolic syndrome. Sequence analysis of cDNA revealed insertion of 14 nucleotides in HTG gene. Polymorphism in Igf2 gene may be responsible for abnormal lipid metabolism in HTG, but its role in blood pressure regulation remains to be elucidated (en)
Title
  • Abnormal Igf 2 gene in Prague hereditary hypertriglyceridemic rats: its relation to blood pressure and plasma lipids
  • Abnormální Igf2 gen u pražských hereditárně hypertenzních potkanů: jeho vztah ke krevnímu tlaku a plasmatickým lipidům (cs)
  • Abnormal Igf 2 gene in Prague hereditary hypertriglyceridemic rats: its relation to blood pressure and plasma lipids (en)
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  • Abnormal Igf 2 gene in Prague hereditary hypertriglyceridemic rats: its relation to blood pressure and plasma lipids
  • Abnormální Igf2 gen u pražských hereditárně hypertenzních potkanů: jeho vztah ke krevnímu tlaku a plasmatickým lipidům (cs)
  • Abnormal Igf 2 gene in Prague hereditary hypertriglyceridemic rats: its relation to blood pressure and plasma lipids (en)
skos:notation
  • RIV/67985823:_____/08:00310367!RIV09-AV0-67985823
http://linked.open...avai/riv/aktivita
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  • P(1M0510), P(GA305/08/0139), Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika
  • 1-2
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  • 354652
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  • RIV/67985823:_____/08:00310367
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  • plasma cholesterol; plasma triglycerides; F2 hybrids (en)
http://linked.open.../riv/klicoveSlovo
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  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [1A28DB1EB344]
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  • Molecular and Cellular Biochemistry
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  • 314
http://linked.open...iv/tvurceVysledku
  • Kuneš, Jaroslav
  • Zicha, Josef
  • Kadlecová, Michaela
  • Dobešová, Zdenka
http://linked.open...ain/vavai/riv/wos
  • 256757200005
http://linked.open...n/vavai/riv/zamer
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  • 0300-8177
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