About: Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related     Goto   Sponge   NotDistinct   Permalink

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  • The effect of thiazide-like diuretic-indapamide on fibrosis development in the left ventricle of young spontaneously hypertensive rats (SHR) was studied in order to assess the involvement of nitric oxide in this process. Indapamide prevented myocardial fibrosis development in SHR, but without affecting collagen type I to type III ratio. Indapamide did not affect NOS activity as well as eNOS and iNOS protein expressions in the left ventricles. Thus indapamide-induced prevention of myocardial fibrosis is not mediated by nitric oxide-related mechanism
  • The effect of thiazide-like diuretic-indapamide on fibrosis development in the left ventricle of young spontaneously hypertensive rats (SHR) was studied in order to assess the involvement of nitric oxide in this process. Indapamide prevented myocardial fibrosis development in SHR, but without affecting collagen type I to type III ratio. Indapamide did not affect NOS activity as well as eNOS and iNOS protein expressions in the left ventricles. Thus indapamide-induced prevention of myocardial fibrosis is not mediated by nitric oxide-related mechanism (en)
Title
  • Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related
  • Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related (en)
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  • Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related
  • Indapamide-induced prevention of myocardial fibrosis in spontaneous hypertension rats is not nitric oxide-related (en)
skos:notation
  • RIV/67985823:_____/07:00331650!RIV10-MSM-67985823
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(1M0510), Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika
  • 6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 425960
http://linked.open...ai/riv/idVysledku
  • RIV/67985823:_____/07:00331650
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  • indapamide; myocardial fibrosis; genetic hypertension (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [CAE1BD45B86E]
http://linked.open...i/riv/nazevZdroje
  • Physiological Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...v/svazekPeriodika
  • 56
http://linked.open...iv/tvurceVysledku
  • Janega, P.
  • Pecháňová, Olga
  • Babál, P.
  • Kojšová, S.
  • Jendeková, L.
http://linked.open...ain/vavai/riv/wos
  • 252358700020
http://linked.open...n/vavai/riv/zamer
issn
  • 0862-8408
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