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  • This work was aimed to evaluate the role of inhibitory Gi proteins and nifedipine-sensitive calcium influx in alpha-adrenergic vasoconstriction in WKY and SHR rats.Pretreatment with nifedipine or PTX reduced both phenylephrine- and clonidine-induced blood pressure responses, the changes being greater on alpha 2-adrenergic vasoconstriction. Our results indicate that Gi proteins and VDCC play an important role in adrenergic vasoconstriction
  • This work was aimed to evaluate the role of inhibitory Gi proteins and nifedipine-sensitive calcium influx in alpha-adrenergic vasoconstriction in WKY and SHR rats.Pretreatment with nifedipine or PTX reduced both phenylephrine- and clonidine-induced blood pressure responses, the changes being greater on alpha 2-adrenergic vasoconstriction. Our results indicate that Gi proteins and VDCC play an important role in adrenergic vasoconstriction (en)
  • Úkolem práce bylo přispět k odhalení úlohy inhibičních Gi proteinů a nifedipin-senzitivního influxu vápníku v alfa-adrenergní vazokonstrikci u WKY a SHR potkanů. Předchozí podání nifedipinu nebo PTX snížilo fenylefrinem- a klonidinem-vyvolanou tlakovou odpověď, změna byla větší u alfa 2-adrenergní vazokonstrikce. Naše výsledky naznačují že Gi proteiny a VDCC hrají důležitou roli v adrenergní vazokonstrikci (cs)
Title
  • In vivo effects of pertussis toxin on adrenergic vasoconstriction
  • In vivo účinek pertussis toxinu na adrenergní vazokonstrikci (cs)
  • In vivo effects of pertussis toxin on adrenergic vasoconstriction (en)
skos:prefLabel
  • In vivo effects of pertussis toxin on adrenergic vasoconstriction
  • In vivo účinek pertussis toxinu na adrenergní vazokonstrikci (cs)
  • In vivo effects of pertussis toxin on adrenergic vasoconstriction (en)
skos:notation
  • RIV/67985823:_____/07:00088967!RIV08-AV0-67985823
http://linked.open.../vavai/riv/strany
  • 76;82
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  • P(1M0510), Z(AV0Z50110509)
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  • 425878
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  • RIV/67985823:_____/07:00088967
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  • inhibitory Gi proteins; nifedipine-sensitive calcium influx; alpha-adrenergic vasoconstriction (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [EB362480EAA3]
http://linked.open...i/riv/mistoVydani
  • Bratislava
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  • Nitric oxide signaling pathways
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  • Kuneš, Jaroslav
  • Pintérová, Mária
  • Zicha, Josef
  • Dobešová, Zdenka
http://linked.open...n/vavai/riv/zamer
number of pages
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  • Advent-Orion
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  • 978-80-8071-094-1
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