About: Antibody formation against beta-tubulin class III in response to brain trauma

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Brain trauma typically leads to neuronal damage and loss. Assuming a transient autoimmune response to debris of the damaged neurones, we have monitored serum titres of IgG and IgM antibodies to beta-tubulin class III (betaTcIII), which is almost exclusively found in neuronal cytoskeletons. In 15 out of 18 patients, the peak of the IgG or IgM antibody titre appeared in the serum within 3 weeks of a brain trauma Brain trauma typically leads to neuronal damage and loss. Assuming a transient autoimmune response to debris of the damaged neurones, we have monitored serum titres of IgG and IgM antibodies to beta-tubulin class III (betaTcIII), which is almost exclusively found in neuronal cytoskeletons. In 15 out of 18 patients, the peak of the IgG or IgM antibody titre appeared in the serum within 3 weeks of a brain trauma (en) Mozkové trauma zpravidla vede k neuronálnímu poškození a ztrátě nervových buněk. Ve studii jsme měřili serové IgG a IgM protilátky proti beta-tubulinu III, který je nalézám téměř výhradně v cytoskeletu neuronů. U 15 z 18 pacientů se sérové protilátky objevily během tří týdnu po mozkovém traumatu (cs)
Title	Antibody formation against beta-tubulin class III in response to brain trauma Formování protilátek proti beta-tubulinu třídy III v odpovědi na poškození mozku (cs) Antibody formation against beta-tubulin class III in response to brain trauma (en)
skos:prefLabel	Antibody formation against beta-tubulin class III in response to brain trauma Formování protilátek proti beta-tubulinu třídy III v odpovědi na poškození mozku (cs) Antibody formation against beta-tubulin class III in response to brain trauma (en)
skos:notation	RIV/67985823:_____/06:00049690!RIV07-MZ0-67985823
http://linked.open.../vavai/riv/strany	213;216
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NR8114), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2007
http://linked.open...aciTvurceVysledku	Kenney, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	465502
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/06:00049690
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	autoantibodies; beta–tubulin; brain injury (en)
http://linked.open.../riv/klicoveSlovo	autoantibodies beta–tubulin brain injury
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[015568ED4955]
http://linked.open...i/riv/nazevZdroje	Brain Research Bulletin
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Detection of antibodies generated as a reaction on demaged neural tissue
http://linked.open...UplatneniVysledku	2006
http://linked.open...v/svazekPeriodika	68
http://linked.open...iv/tvurceVysledku	Kenney, Jana Škoda, D. Bojar, M. Cvachovec, K. Romportl, D. Bäurle, J. Glosová, L. Kranda, K. Pelichovská, M.
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
issn	0361-9230
number of pages	4 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Antibody formation against beta-tubulin class III in response to brain trauma Antibody formation against beta-tubulin class III in response to brain trauma

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