About: Effect of free radical spin trap N-tert-butyl-alpha-phenylnitrone (PBN) on seizures induced in immature rats by homocysteic acid

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The severity of seizures induced in immature rats by homocysteic acid was not significantly influenced by PBN treatment. Nevertheless, PBN has a clear -cut protective effect, evident as both the improved recovery of brain energy status and as a significant attenuation of neuronal degeneration associated with this model of seizures The severity of seizures induced in immature rats by homocysteic acid was not significantly influenced by PBN treatment. Nevertheless, PBN has a clear -cut protective effect, evident as both the improved recovery of brain energy status and as a significant attenuation of neuronal degeneration associated with this model of seizures (en) Podání PBN neovlivnilo intenzitu křečí vyvolaných u mláďat kyselinou homocysteovou. PBN měl však výrazný neuroprotektivní účinek: došlo k obnově snížených hladin ATP v hipokampu a k signifikantnímu snženi neuronálního poškození v mnoha oblastech mozku. (cs)
Title	Effect of free radical spin trap N-tert-butyl-alpha-phenylnitrone (PBN) on seizures induced in immature rats by homocysteic acid Vliv N-tert-butyl-alfa-fenyl nitronu (PBN), vychytávače volných radikálů, na křeče vyvolané u mláďat laboratorního potkana kyselinou homocysteovou (cs) Effect of free radical spin trap N-tert-butyl-alpha-phenylnitrone (PBN) on seizures induced in immature rats by homocysteic acid (en)
skos:prefLabel	Effect of free radical spin trap N-tert-butyl-alpha-phenylnitrone (PBN) on seizures induced in immature rats by homocysteic acid Vliv N-tert-butyl-alfa-fenyl nitronu (PBN), vychytávače volných radikálů, na křeče vyvolané u mláďat laboratorního potkana kyselinou homocysteovou (cs) Effect of free radical spin trap N-tert-butyl-alpha-phenylnitrone (PBN) on seizures induced in immature rats by homocysteic acid (en)
skos:notation	RIV/67985823:_____/06:00041026!RIV07-AV0-67985823
http://linked.open.../vavai/riv/strany	105;119
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA309/02/1238), P(GA309/05/2015), Z(AV0Z50110509), Z(AV0Z50200510)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2007
http://linked.open...aciTvurceVysledku	Mareš, Pavel Kubová, Hana Otáhal, Jakub Druga, Rastislav Folbergrová, Jaroslava
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	473056
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/06:00041026
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	DL-homocysteic acid induced seizures; neuronal damage; protection (en)
http://linked.open.../riv/klicoveSlovo	protection DL-homocysteic acid induced seizures neuronal damage
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[FAAB424F2BA4]
http://linked.open...i/riv/nazevZdroje	Experimental Neurology
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Study of potential protective effects of selected drugs on the development of epileptogenesis following status epilepticus induced in immature rats Mechanisms and consequences of brain damage associated with seizure activity in immature rats
http://linked.open...UplatneniVysledku	2006
http://linked.open...v/svazekPeriodika	201
http://linked.open...iv/tvurceVysledku	Mareš, Pavel Kubová, Hana Otáhal, Jakub Druga, Rastislav Folbergrová, Jaroslava Haugvicová, Renata
http://linked.open...n/vavai/riv/zamer	Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka Microorganisms in Research and Biotechnology
issn	0014-4886
number of pages	15 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Effect of free radical spin trap N-tert-butyl-alpha-phenylnitrone (PBN) on seizures induced in immature rats by homocysteic acid Effect of free radical spin trap N-tert-butyl-alpha-phenylnitrone (PBN) on seizures induced in immature rats by homocysteic acid

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