About: Mucoadhesive films as perspective oral dosage form

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Mucoadhesion is a specific phenomenon of creating bonds during intimate contact between biological surfaces covered by mucus layer and a mucoadhesive material. In recent years come to the forefront of interest in the pharmaceutical industry modern dosage forms based on this specific process. Films (discs, patches) composed of mucoadhesive polymers (cellulose derivatives, polyacrylates, polyoxyethylene, etc.) prepared by established methods (solvent casting, hot melt extrusion, etc.) could be perspective candidates for oral administration of many drugs due to their flexibility and comfortable use. In addition, they can circumvent the relatively short residence time of conventional oral dosage forms on the mucosa and provide a precisely measured drug dose to the application site. Moreover, they can also help to protect the wound surface, thus helping to reduce pain and improve effectiveness of the therapy. The aim of this article is to give an overview about principles of creation of mucoadhesive bonds and about novel dosage form ? mucoadhesive films in terms of their composition, preparation and practical usage. Mucoadhesion is a specific phenomenon of creating bonds during intimate contact between biological surfaces covered by mucus layer and a mucoadhesive material. In recent years come to the forefront of interest in the pharmaceutical industry modern dosage forms based on this specific process. Films (discs, patches) composed of mucoadhesive polymers (cellulose derivatives, polyacrylates, polyoxyethylene, etc.) prepared by established methods (solvent casting, hot melt extrusion, etc.) could be perspective candidates for oral administration of many drugs due to their flexibility and comfortable use. In addition, they can circumvent the relatively short residence time of conventional oral dosage forms on the mucosa and provide a precisely measured drug dose to the application site. Moreover, they can also help to protect the wound surface, thus helping to reduce pain and improve effectiveness of the therapy. The aim of this article is to give an overview about principles of creation of mucoadhesive bonds and about novel dosage form ? mucoadhesive films in terms of their composition, preparation and practical usage. (en)
Title	Mucoadhesive films as perspective oral dosage form Mucoadhesive films as perspective oral dosage form (en)
skos:prefLabel	Mucoadhesive films as perspective oral dosage form Mucoadhesive films as perspective oral dosage form (en)
skos:notation	RIV/62157124:16370/13:43872193!RIV14-MZ0-16370___
http://linked.open...avai/predkladatel	Farmaceutická fakulta
http://linked.open...avai/riv/aktivita	I P S
http://linked.open...avai/riv/aktivity	I, P(NT11396), S
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Landová, Hana Gajdziok, Jan Vetchý, David
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Veterinární a farmaceutická univerzita Brno / Farmaceutická fakulta
http://linked.open...dnocenehoVysledku	89973
http://linked.open...ai/riv/idVysledku	RIV/62157124:16370/13:43872193
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	oral mucosa, mucoadhesion principles, mucoadhesive dosage forms, films, patches, discs (en)
http://linked.open.../riv/klicoveSlovo	discs mucoadhesion principles mucoadhesive dosage forms patches oral mucosa films
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[2CF0A51EF89B]
http://linked.open...i/riv/nazevZdroje	Česká a slovenská farmacie
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Mucoadhesive patches intended to dressing of mucosal defects of the oral cavity
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	62
http://linked.open...iv/tvurceVysledku	Gajdziok, Jan Landová, Hana Vetchý, David Daněk, Zdeněk Štembírek, Jan
issn	1210-7816
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	16370

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