About: Chemoprotective and toxic potentials of synthetic and natural chalcones and dihydrochalcones in vitro.     Goto   Sponge   NotDistinct   Permalink

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  • In this study, a series of 31 chalcones and their corresponding dihydro derivatives were tested for their ability to inhibit lipid peroxidation and EROD activity in rat hepatic microsomes. Effects on gap junctional intercellular communication (GJIC) were determined in WB-F344 cells. Some of the chalcones might be promising chemoprotective compounds against CYP1A activity, and partly also against oxidative damage without inducing adverse effects, such as GJIC inhibition.
  • In this study, a series of 31 chalcones and their corresponding dihydro derivatives were tested for their ability to inhibit lipid peroxidation and EROD activity in rat hepatic microsomes. Effects on gap junctional intercellular communication (GJIC) were determined in WB-F344 cells. Some of the chalcones might be promising chemoprotective compounds against CYP1A activity, and partly also against oxidative damage without inducing adverse effects, such as GJIC inhibition. (en)
Title
  • Chemoprotective and toxic potentials of synthetic and natural chalcones and dihydrochalcones in vitro.
  • Chemoprotective and toxic potentials of synthetic and natural chalcones and dihydrochalcones in vitro. (en)
skos:prefLabel
  • Chemoprotective and toxic potentials of synthetic and natural chalcones and dihydrochalcones in vitro.
  • Chemoprotective and toxic potentials of synthetic and natural chalcones and dihydrochalcones in vitro. (en)
skos:notation
  • RIV/62157124:16370/05:00000011!RIV10-MSM-16370___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(LN00A016), Z(MSM 163700003), Z(MZE0002716201)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 515184
http://linked.open...ai/riv/idVysledku
  • RIV/62157124:16370/05:00000011
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • chalcons (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • IE - Irsko
http://linked.open...ontrolniKodProRIV
  • [D82FB84BBF1C]
http://linked.open...i/riv/nazevZdroje
  • Toxicology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 1
http://linked.open...iv/tvurceVysledku
  • Kubínová, Renáta
  • Marek, Radek
  • Suchý, Václav
  • Vondráček, Jan
  • Machala, Miroslav
  • Lunerová, Kamila
  • Forejtníková, Hana
  • Jankovská, Dagmar
  • Kareš, Rudolf
http://linked.open...ain/vavai/riv/wos
  • 000226923000008
http://linked.open...n/vavai/riv/zamer
issn
  • 0300-483X
number of pages
http://localhost/t...ganizacniJednotka
  • 16370
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