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rdf:type
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rdfs:seeAlso
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Description
| - Combination of fluorescence techniques and molecular docking was used to monitor interaction of Na,K-ATPase and its large cytoplasmic loop connecting fourth and fifth transmembrane helices (C45) with fluorone dyes (i.e. eosin Y, 5(6)-carboxyeosin, rose bengal, fluorescein, and erythrosine B). Our data suggested that there are at least two binding sites for all used fluorone dyes, except of 5(6)-carboxyeosin. The first binding site is located on C45 loop, and it is sensitive to the presence of nucleotide. The other site is located on the extracellular part of the enzyme, and it is sensitive to the presence of Na + or K+ ions.
- Combination of fluorescence techniques and molecular docking was used to monitor interaction of Na,K-ATPase and its large cytoplasmic loop connecting fourth and fifth transmembrane helices (C45) with fluorone dyes (i.e. eosin Y, 5(6)-carboxyeosin, rose bengal, fluorescein, and erythrosine B). Our data suggested that there are at least two binding sites for all used fluorone dyes, except of 5(6)-carboxyeosin. The first binding site is located on C45 loop, and it is sensitive to the presence of nucleotide. The other site is located on the extracellular part of the enzyme, and it is sensitive to the presence of Na + or K+ ions. (en)
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Title
| - Fluorone dyes have binding sites on both cytoplasmic and extracellular domains of Na,K-ATPase
- Fluorone dyes have binding sites on both cytoplasmic and extracellular domains of Na,K-ATPase (en)
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skos:prefLabel
| - Fluorone dyes have binding sites on both cytoplasmic and extracellular domains of Na,K-ATPase
- Fluorone dyes have binding sites on both cytoplasmic and extracellular domains of Na,K-ATPase (en)
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skos:notation
| - RIV/61989592:15310/13:33145503!RIV14-GA0-15310___
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http://linked.open...avai/predkladatel
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(EE2.3.20.0057), P(GAP301/10/0883), P(GPP205/11/P319)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15310/13:33145503
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Time-resolved fluorescence; Na,K-ATPase; Fluorone dyes; Fluorescence quenching; C45 loop; Binding sites (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Biochimica et Biophysica Acta - Biomembranes
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Kubala, Martin
- Berka, Karel
- Havlíková, Marika
- Huličiak, Miroslav
- Bazgier, Václav
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1016/j.bbamem.2012.10.029
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http://localhost/t...ganizacniJednotka
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